Skinner marries Eve Blue, whom he met at the University of Minnesota. Eve was an aspiring writer. Their marriage lasted until her death in 1977 and was reportedly a supportive and stable partnership.

Skinner and Eve welcome their first daughter, Julie Vargas, who later became an educational psychologist and advocate for behavior analysis.

Skinner and Eve welcome their second daughter, Deborah Skinner Buzan. Deborah's upbringing in the 'Air-Crib' generated some controversy.

Skinner's wife, Eve Blue, passes away. This was a significant loss for Skinner.

Skinner remained dedicated to his work and family throughout his life. He maintained close relationships with his daughters and grandchildren and continued to pursue his research and writing until his death.