Barbarikon (Ancient Greek: Βαρβαρικόν) was the name of a sea port near the modern-day city of Karachi, Sindh, Pakistan, important in the ancient era of the Indian subcontinent in Indian Ocean trade. The port is considered one of the premiere ports regarding the interaction between ancient India with the Middle East and Mediterranean world. It comes from the Greek word of the term (also in Latin, barbaricum), designating areas outside the Greco-Roman world.

It may have been a translation from Sumerian word Meluhha for the Sindh from which the Sanskrit word for barbarian, Mleccha derives.

Barbarikon is mentioned briefly in the Periplus of the Erythraean Sea:

Its principal function beyond supplying its immediate hinterland was as a transshipment port for supplies of Persian turquoise and Afghan lapis lazuli, to be carried overland to Egypt.