Blade Runner: Original Motion Picture Soundtrack is the soundtrack for Ridley Scott's 1982 science-fiction noir film Blade Runner, composed by Greek electronic musician Vangelis. It has received acclaim as an influential work in the history of electronic music and one of Vangelis's best works. It was nominated in 1983 for a BAFTA and Golden Globe for best original score. The score evokes the film's bleak futurism with an emotive synthesizer-based sound, drawing on the jazz scores of classic film noir as well as Middle Eastern texture and neo-classical elements.

The official release of the soundtrack was delayed for over a decade. The first 1994 release omitted much of the film's score and included compositions not used in the film. A 25th anniversary edition released in 2007 included further unreleased material and a disc of new music inspired by the film. Various bootleg recordings containing more comprehensive versions of the score, as well as superior sound quality to the original 1994 release, have widely circulated.

An orchestral rendition of the soundtrack was released in 1982 by the New American Orchestra, but disowned by both Vangelis and director Scott.

Vangelis recorded, mixed and produced the score for Blade Runner in his London recording space Nemo Studios in 1982. He crafted the score on an ad-hoc basis by viewing videotapes of scenes from the film in the studio, and then improvising pieces in synchronisation with the images on the screen. He also applied the use of some Foley techniques, using synthesisers to produce diegetic and non-diegetic sounds. The album features vocals from Demis Roussos and saxophone by Dick Morrissey on "Love Theme". The track "Memories of Green" from Vangelis' 1980 album See You Later was also used.

The most prominent synthesiser used in the score was the Yamaha CS-80, which can be prominently heard in the opening scenes. Other synthesisers employed by Vangelis included four Roland instruments: the ProMars, the Jupiter-4, the CR-5000 drum machine, and the VP-330 Vocoder Plus; a Sequential Circuits Prophet-10; a Yamaha GS1 FM synthesizer; and an E-mu Emulator sampler. A Steinway grand piano, a Yamaha CP-80 electric grand and a modified Fender Rhodes were also used. He also utilised a variety of traditional instruments, including gamelan, glockenspiel, gong, snare drum, timpani and tubular bells.

In 1994, an official recording of Vangelis' score was released by East West (Warner Music) in the UK and by Atlantic Records in the US. The album reached the #20 position in the UK album charts. In 2013 it reached #14 on the Billboard Vinyl Albums chart. It has been variously described as "influential and mythical", "incredible and pristine", "evocative", and "the pinnacle of synthesiser soundtracks". AllMusic labeled the score as "bleak and electronically chilling as the film itself" and praised Vangelis for creating "haunting soundscapes with whispered subtexts and sweeping revelations".

This release omits much of the film's original music and cues, and features compositions which were not present in the film. The accompanying booklet featured this explanation by Vangelis:

Most of the music contained in this album originates from recordings I made in London in 1982, whilst working on the score for the film Blade Runner. Finding myself unable to release these recordings at the time; it is with great pleasure that I am able to do so now. Some of the pieces contained will be known to you from the Original Soundtrack of the film, whilst others are appearing here for the first time. Looking back at Ridley Scott's powerful and evocative pictures left me as stimulated as before, and made the recompiling of this music, today, an enjoyable experience. (Vangelis, Athens, April 1994)