Application software is software that is intended for end-user use – not operating, administering or programming a computer. An application (app, application program, software application) is any program that can be categorized as application software. Application is a subjective classification that is often used to differentiate from system and utility software.

The abbreviation app became popular with the 2008 introduction of the iOS App Store, to refer to applications for mobile devices such as smartphones and tablets. Later, with the release of the Mac App Store in 2010 and the Windows Store in 2011, it began to be used to refer to end-user software in general, regardless of platform.

Applications may be bundled with the computer and its system software or published separately. Applications may be proprietary or open-source.

When used as an adjective, application can have a broader meaning than that described in this article. For example, concepts such as application programming interface (API), application server, application virtualization, application lifecycle management and portable application refer to programs and software in general.

The distinction between system and application software is subjective and has been the subject of controversy. For example, one of the key questions in the United States v. Microsoft Corp. antitrust trial was whether Microsoft's Internet Explorer web browser was part of its Windows operating system or a separate piece of application software. As another example, the GNU/Linux naming controversy is, in part, due to disagreement about the relationship between the Linux kernel and the operating systems built over this kernel. In some types of embedded systems, the application software and the operating system software may be indistinguishable by the user, as in the case of software used to control a VCR, DVD player, or microwave oven. The above definitions may exclude some applications that may exist on some computers in large organizations. For an alternative definition of an app: see Application Portfolio Management.

A killer application (killer app, coined in the late 1980s) is an application that is so popular that it causes demand for its host platform to increase. For example, VisiCalc was the first modern spreadsheet software for the Apple II and helped sell the then-new personal computers into offices. For the BlackBerry, it was its email software.

As software suite consists of multiple applications bundled together. They usually have related functions, features, and user interfaces, and may be able to interact with each other, e.g. open each other's files. Business applications often come in suites, e.g. Microsoft Office, LibreOffice and iWork, which bundle together a word processor, a spreadsheet, etc.; but suites exist for other purposes, e.g. graphics or music.

As there so many applications and since their attributes vary so dramatically, there are many different ways to classify them.