The Harlem Renaissance was an intellectual and cultural movement of African-American music, dance, art, fashion, literature, theater, politics, and scholarship centered in Harlem, Manhattan, New York City, spanning the 1920s and 1930s. At the time, it was known as the "New Negro Movement", named after The New Negro, a 1925 anthology edited by Alain Locke. The movement also included the new African-American cultural expressions across the urban areas in the Northeastern United States and the Midwestern United States affected by a renewed militancy in the general struggle for civil rights, combined with the Great Migration of African-American workers fleeing the racist conditions of the Jim Crow Deep South, as Harlem was the final destination of the largest number of those who migrated north.

Though geographically tied to Harlem, few of the associated visual artists lived in the area itself, while those who did (such as Aaron Douglas) had migrated elsewhere by the end of World War II. Many francophone black writers from African and Caribbean colonies who lived in Paris, France, were also influenced by the movement. Harlem had also seen significant Black immigration from British, French and other colonies in the Caribbean. The zenith of this "flowering of Negro literature", as James Weldon Johnson described the Harlem Renaissance, took place between approximately 1924—when Opportunity: A Journal of Negro Life hosted a party for black writers where many white publishers were in attendance—and 1929, the year of the stock-market crash and the beginning of the Great Depression. The Harlem Renaissance is considered to have been a creative crucible for African-American art-making and its institutionalisation within white-dominated museums and cultural institutions.

Until the end of the Civil War, the majority of African Americans had been enslaved and lived in the South. During the Reconstruction Era, the emancipated African Americans began to strive for civic participation, political equality, and economic and cultural self-determination. Soon after the end of the Civil War, the Ku Klux Klan Act of 1871 gave rise to speeches by African-American congressmen addressing this bill. By 1875, sixteen African Americans had been elected and served in Congress and gave numerous speeches with their newfound civil empowerment.

The Ku Klux Klan Act of 1871 was followed by the passage of the Civil Rights Act of 1875, part of Reconstruction legislation by Republicans. During the mid-to-late 1870s, racist whites organized in the Democratic Party launched a murderous campaign of racist terrorism to regain political power throughout the South. From 1890 to 1908, they proceeded to pass legislation that disenfranchised most African Americans and many poor whites, trapping them without representation. They established white supremacist regimes of Jim Crow segregation in the South and one-party block voting behind Southern Democrats.

Democratic Party politicians (many having been former slaveowners and political and military leaders of the Confederacy) conspired to deny African Americans their exercise of civil and political rights by terrorizing black communities with lynch mobs and other forms of vigilante violence as well as by instituting a convict labor system that forced many thousands of African Americans back into unpaid labor in mines, plantations and on public works projects such as roads and levees. Convict laborers were typically subject to brutal forms of corporal punishment, overwork and disease from unsanitary conditions. Death rates were extraordinarily high. While a small number of African Americans were able to acquire land shortly after the Civil War, most were exploited as sharecroppers. Whether sharecropping or on their own acreage, most of the black population was closely financially dependent on agriculture. This added another impetus for the Migration: the arrival of the boll weevil. The beetle eventually came to waste 8% of the country's cotton yield annually and thus disproportionately impacted this part of America's citizenry. As life in the South became increasingly difficult, African Americans began to migrate north in great numbers.

Most of the future leading lights of what was to become known as the "Harlem Renaissance" movement arose from a generation that had memories of the gains and losses of Reconstruction after the Civil War. Sometimes their parents, grandparents—or they themselves—had been slaves. Their ancestors had sometimes benefited by paternal investment in cultural capital, including better-than-average education.

Many in the Harlem Renaissance were part of the early 20th-century Great Migration out of the South into the African-American neighborhoods of the Northeast and Midwest. African Americans sought a better standard of living and relief from the institutionalized racism in the South. Others were people of African descent from racially stratified communities in the Caribbean who came to the United States hoping for a better life. Uniting most of them was their convergence in Harlem.

During the early 20th century, Harlem was a destination for migrants from around the country, attracting both people from the South seeking work and an educated class who made the area a center of culture, as well as a growing "Negro" middle class. These people were looking for a fresh start in life and this was a good place to go. The district had originally been developed in the 19th century as an exclusive suburb for the white middle and upper middle classes; its affluent beginnings led to the development of stately houses, grand avenues, and world-class amenities such as the Polo Grounds and the Harlem Opera House. During the enormous influx of European immigrants in the late 19th century, the once exclusive district was abandoned by the white middle class, who moved farther north.