Lille OSC in European football

Page is a work in progress.^[1]

As of match played 2 October 2025

Latin Cup and 1967 Intertoto Cup excluded because they weren’t organised by UEFA.

Legend: Pld = Played; W = Won; D = Drawn; L = Lost; GF = Goals For; GA = Goals Against; GD = Goal Difference.

Season	Competition	Round	Opponent	Home	Away	Aggregate	Result[2]
1951	Latin Cup	Semi-finals	Sporting CP	1–1 (a.e.t.)	6–4 (a.e.t.)*	—
		Final	Milan	0–5
1967	Intertoto Cup	Group stage	Sion	3–1	0–0	3rd
			Beerschot	2–2	0–1
			Groningen	3–1	2–1
2001–02	UEFA Champions League	Third qualifying round	Parma	2–0	0–1	2–1
		Group G	Manchester United	1–1	0–1	3rd
			Olympiacos	3–1	1–2
			Deportivo La Coruña	1–1	1–1
	UEFA Cup	Third round	Fiorentina	1–0	2–0	3–0
		Fourth round	Borussia Dortmund	1–1	0–0	1–1 (a)
2004–05	UEFA Intertoto Cup	Third round	Dinamo Minsk	2–1	2–2	4–3
		Semi-finals	Slaven Belupo	3–0	1–1	4–1
		Finals	União de Leiria	0–0	2–0 (a.e.t.)	2–0
	UEFA Cup	First round	Shelbourne	2–2	2–0	4–2
		Group H	Alemannia Aachen	—	0–1	1st
			Zenit Saint Petersburg	2–1	—
			AEK Athens	—	2–1
			Sevilla	1–0	—
		Round of 32	Basel	2–0	0–0	2–0
		Round of 16	Auxerre	0–1	0–0	0–1
2005–06	UEFA Champions League	Group D	Benfica	0–0	0–1	3rd
			Villarreal	0–0	0–1
			Manchester United	1–0	0–0
	UEFA Cup	Round of 32	Shakhtar Donetsk	3–2	0–0	3–2
		Round of 16	Sevilla	1–0	0–2	1–2
2006–07	UEFA Champions League	Third qualifying round	Rabotnički	3–0	1–0	4–0
		Group H	Anderlecht	2–2	1–1	2nd
			AEK Athens	3–1	0–1
			Milan	0–0	0–2
		Round of 16	Manchester United	0–1	0–1	0–2
2009–10	UEFA Europa League	Third qualifying round	Sevojno	2–0	2–0	4–0
		Play-off round	Genk	2–1	4–2	6–3
		Group B	Valencia	1–1	1–3	2nd
			Slavia Prague	3–1	5–1
			Genoa	3–0	2–3
		Round of 32	Fenerbahçe	2–1	1–1	3–2
		Round of 16	Liverpool	1–0	0–3	1–3
2010–11	UEFA Europa League	Play-off round	Vaslui	0–0	2–0	2–0
		Group C	Sporting CP	1–2	0–1	2nd
			Gent	3–0	1–1
			Levski Sofia	1–0	2–2
		Round of 32	PSV Eindhoven	2–2	1–3	3–5
2011–12	UEFA Champions League	Group B	CSKA Moscow	2–2	2–0	4th
			Trabzonspor	0–0	1–1
			Internazionale	0–1	1–2
2012–13	UEFA Champions League	Play-off round	Copenhagen	2–0	0–1	2–1
		Group F	BATE Borisov	1–3	2–0	4th
			Valencia	0–1	0–2
			Bayern Munich	0–1	1–6
2014–15	UEFA Champions League	Third qualifying round	Grasshoppers	1–1	2–0	3–1
		Play-off round	Porto	0–1	0–2	0–3
	UEFA Europa League	Group H	Krasnodar	1–1	1–1	4th
			VfL Wolfsburg	1–1	1–5
			Everton	0–0	0–3
2016–17	UEFA Europa League	Third qualifying round	Gabala	1–1	0–1	1–2
2019–20	UEFA Champions League	Group H	Ajax	0–2	0–3	4th
			Chelsea	0–2	1–2
			Valencia	1–1	1–4
2020–21	UEFA Europa League	Group H	Sparta Prague	2–1	4–1	2nd
			Celtic	2–2	2–3
			Milan	1–1	3–0
		Round of 32	Ajax	1–2	1–2	2–4
2021–22	UEFA Champions League	Group G	VfL Wolfsburg	0–0	3–1	1st
			Red Bull Salzburg	1–0	1–2
			Sevilla	0–0	2–1
		Round of 16	Chelsea	1–2	0–2	1–4
2023–24	UEFA Europa Conference League	Play-off round	Rijeka	2–1	1–1 (a.e.t.)	3–2
		Group A	Olimpija Ljubljana	2–0	2–0	1st
			KÍ	3–0	0–0
			Slovan Bratislava	2–1	1–1
		Round of 16	Sturm Graz	1–1	3–0	4–1
		Quarter-finals	Aston Villa	2–1 (a.e.t.)	1–2	3–3 (3–4 p)
2024–25	UEFA Champions League	Third qualifying round	Fenerbahçe	2–1	1–1 (a.e.t.)	3–2
		Play-off round	Slavia Prague	2–0	1–2	3–2
		League phase	Sporting CP	—	0–2	7th
			Real Madrid	1–0	—
			Atlético Madrid	—	3–1
			Juventus	1–1	—
			Bologna	—	2–1
			Sturm Graz	3–2	—
			Liverpool	—	1–2
			Feyenoord	6–1	—
		Round of 16	Borussia Dortmund	1–2	1–1	2–3
2025–26	UEFA Europa League	League phase	Brann	2–1	—
			Roma	—	1–0
			PAOK		—
			Red Star Belgrade	—
			Dinamo Zagreb		—
			Young Boys	—
			Celta Vigo	—
			SC Freiburg		—

* Replay instead of home and away tie.