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Lipid profile

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Lipid profile

A lipid profile or lipid panel is a panel of blood tests used to find abnormalities in blood lipid ( such as cholesterol and triglycerides) concentrations.[not verified in body] The results of this test can identify certain genetic diseases and can determine approximate risks for cardiovascular disease, certain forms of pancreatitis, and other diseases.

Lipid panels are usually ordered as part of a physical exam, along with other panels such as the complete blood count (CBC) and basic metabolic panel (BMP).[not verified in body]

A lipid profile report typically includes:

LDL is not usually actually measured, but calculated from the other three using the Friedewald equation. A laboratory can optionally calculate the two extra values from the report:

Recommendations for cholesterol testing come from the Adult Treatment Panel (ATP) III guidelines, and are based on many large clinical studies, such as the Framingham Heart Study.[citation needed]

For healthy adults with no cardiovascular risk factors, the ATP III guidelines recommend screening once every five years. A lipid profile may also be ordered at regular intervals to evaluate the success of lipid-lowering drugs such as statins.[citation needed]

In the pediatric and adolescent population, lipid testing is not routinely performed. However, the American Academy of Pediatrics and the National Heart, Lung, and Blood Institute (NHLBI) recommend that children aged 9–11 be screened once for severe cholesterol abnormalities. This screening can be valuable to detect genetic diseases such as familial hypercholesterolemia that can be lethal if not treated early.[citation needed]

Traditionally, most laboratories have required patients to fast for 9–12 hours before screening. However, studies have questioned the utility of fasting before lipid panels, and some diagnostic labs routinely accept non-fasting samples.

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