Vesta (minor-planet designation: 4 Vesta) is one of the largest objects in the asteroid belt, with a mean diameter of 525 kilometres (326 mi). It was discovered by the German astronomer Heinrich Wilhelm Matthias Olbers on 29 March 1807 and is named after Vesta, the virgin goddess of home and hearth from Roman mythology.

Vesta is thought to be the second-largest asteroid, both by mass and by volume, after the dwarf planet Ceres. Measurements give it a nominal volume only slightly larger than that of Pallas (about 5% greater), but it is 25% to 30% more massive. It constitutes an estimated 9% of the mass of the asteroid belt. Vesta is the only known remaining rocky protoplanet of the kind that formed the terrestrial planets. Numerous fragments of Vesta were ejected by collisions one and two billion years ago that left two enormous craters occupying much of Vesta's southern hemisphere. Debris from these events has fallen to Earth as howardite–eucrite–diogenite (HED) meteorites, which have been a rich source of information about Vesta.

Vesta is the brightest asteroid visible from Earth. It is regularly as bright as magnitude 5.1, at which times it is faintly visible to the naked eye. Its maximum distance from the Sun is slightly greater than the minimum distance of Ceres from the Sun, although its orbit lies entirely within that of Ceres.

NASA's Dawn spacecraft entered orbit around Vesta on 16 July 2011 for a one-year exploration and left the orbit of Vesta on 5 September 2012 en route to its final destination, Ceres. Researchers continue to examine data collected by Dawn for additional insights into the formation and history of Vesta.

Heinrich Olbers discovered Pallas in 1802, the year after the discovery of Ceres. He proposed that the two objects were the remnants of a destroyed planet. He sent a letter with his proposal to the British astronomer William Herschel, suggesting that a search near the locations where the orbits of Ceres and Pallas intersected might reveal more fragments. These orbital intersections were located in the constellations of Cetus and Virgo. Olbers commenced his search in 1802, and on 29 March 1807 he discovered Vesta in the constellation Virgo—a coincidence, because Ceres, Pallas, and Vesta are not fragments of a larger body. Because the asteroid Juno had been discovered in 1804, this made Vesta the fourth object to be identified in the region that is now known as the asteroid belt. The discovery was announced in a letter addressed to German astronomer Johann H. Schröter dated 31 March. Because Olbers already had credit for discovering a planet (Pallas; at the time, the asteroids were considered to be planets), he gave the honor of naming his new discovery to German mathematician Carl Friedrich Gauss, whose orbital calculations had enabled astronomers to confirm the existence of Ceres, the first asteroid, and who had computed the orbit of the new planet in the remarkably short time of 10 hours. Gauss decided on the Roman virgin goddess of home and hearth, Vesta.

Vesta was the fourth asteroid to be discovered, hence the number 4 in its formal designation. The name Vesta, or national variants thereof, is in international use with two exceptions: Greece and China. In Greek, the name adopted was the Hellenic equivalent of Vesta, Hestia (4 Εστία); in English, that name is used for 46 Hestia (Greeks use the name "Hestia" for both, with the minor-planet numbers used for disambiguation). In Chinese, Vesta is called the 'hearth-god(dess) star', 灶神星 Zàoshénxīng, naming the asteroid for Vesta's role in mythology, similar to the Chinese names of Uranus, Neptune, and Pluto.

Upon its discovery, Vesta was, like Ceres, Pallas, and Juno before it, classified as a planet and given a planetary symbol. The symbol represented the altar of Vesta with its sacred fire and was designed by Gauss. In Gauss's conception, now obsolete, this was drawn . His form was encoded in Unicode 17.0 as U+1F777 🝷. The asteroid symbols were gradually retired from astronomical use after 1852, but the symbols for the first four asteroids were resurrected for astrology in the 1970s. The abbreviated modern astrological variant of the Vesta symbol is (U+26B6 ⚶).

After the discovery of Vesta, no further objects were discovered for 38 years, and during this time the Solar System was thought to have eleven planets. However, in 1845, new asteroids started being discovered at a rapid pace, and by 1851 there were fifteen, each with its own symbol, in addition to the eight major planets (Neptune had been discovered in 1846). It soon became clear that it would be impractical to continue inventing new planetary symbols indefinitely, and some of the existing ones proved difficult to draw quickly. That year, the problem was addressed by Benjamin Apthorp Gould, who suggested numbering asteroids in their order of discovery, and placing this number in a disk (circle) as the generic symbol of an asteroid. Thus, the fourth asteroid, Vesta, acquired the generic symbol ④. This was soon coupled with the name into an official number–name designation, ④ Vesta, as the number of minor planets increased. By 1858, the circle had been simplified to parentheses, (4) Vesta, which were easier to typeset. Other punctuation, such as 4) Vesta and 4, Vesta, was also briefly used, but had more or less completely died out by 1949.