Mina J. Bissell was born in Tehran, Iran. Her early life was shaped by a rich cultural background and a family that valued education, particularly for women, at a time when such opportunities were not always readily available.

Her upbringing emphasized language skills and a classical education, fostering a deep appreciation for learning. This early academic rigor instilled in her a strong foundation for future scientific pursuits.

At the age of 16, Bissell moved to the United States to pursue higher education, reflecting her family's commitment to providing her with the best possible opportunities. This transatlantic move marked a significant transition in her life.

Bissell earned her Bachelor of Arts degree in Chemistry from Radcliffe College, a testament to her early aptitude for the sciences. This marked a pivotal moment as she formally began her scientific career.

She obtained her Ph.D. in Microbiology and Molecular Genetics from Harvard University, solidifying her expertise in the field and demonstrating her commitment to advanced scientific research. Her doctoral work provided her with critical thinking, analysis, and experimental design skills that she carried throughout her research career.