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List of combined sex-hormonal preparations
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This is a list of known combined sex-hormonal formulations. Brand names and developmental code names are in parentheses.
Androgens
[edit]Injection
[edit]Marketed
[edit]- Nandrolone decanoate/nandrolone phenylpropionate (Dinandrol)
- Testosterone propionate/testosterone isocaproate/testosterone caproate (Androteston PP)[1]
- Testosterone propionate/testosterone enanthate/testosterone undecylenate (Durasteron)
- Testosterone propionate/testosterone enanthate (Testoviron Depot)
- Testosterone propionate/testosterone ketolaurate (Testosid Depot)
- Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (Sustanon 100)
- Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone caproate (Omnadren 250)
- Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate (Sustanon 250)
- Testosterone propionate/testosterone valerate/testosterone undecylenate (Triolandren)
- Testosterone propionate/testosterone cypionate/prasterone (Sten)
Veterinary
[edit]Marketed
[edit]Estrogens
[edit]Oral
[edit]Marketed
[edit]- Conjugated estriol (Emmenin, Progynon)
- Conjugated estrogens (Premarin)
- Esterified estrogens (Estratab, Menest)
- Estradiol/estrone/estriol (Hormonin)
- Ethinylestradiol/dienestrol (Foxinette)
Injection
[edit]Marketed
[edit]- Estradiol benzoate/estradiol phenylpropionate (Dimenformon Prolongatum)
Never marketed
[edit]Progestogens
[edit]Androgens and estrogens
[edit]Oral
[edit]Marketed
[edit]- Chlorotrianisene/methyltestosterone (Tace mit Androgen)[1]
- Conjugated estrogens/methyltestosterone (Premarin with Methyltestosterone)
- Dienestrol/methyltestosterone (Estan, Lucidon)
- Dienestrol diacetate/methyltestosterone (Farmatest)
- Diethylstilbestrol/methyltestosterone (Tylosterone)
- Esterified estrogens/methyltestosterone (Covaryx, Eemt, Essian, Estratest, Menogen, Syntest)
- Ethinylestradiol/methyltestosterone (Climatone, Dumone, Duotrone, Estandron, Femandren, Femovirin, Gynetone, Lynandron, Mepilin, Mixogen, Primodian)[1][2]
- Methylestradiol/methyltestosterone (Klimanosid)[2]
- Methylestradiol/methyltestosterone/reserpine (Klimanosid R)[1]
Injection
[edit]Marketed
[edit]- Estradiol benzoate/testosterone propionate (Bothermon)
- Estradiol benzoate/estradiol dienanthate/testosterone enanthate benzilic acid hydrazone (Climacteron, Lactimex, Lactostat)
- Estradiol benzoate/estradiol phenylpropionate/testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (Estandron Prolongatum, Lynandron Prolongatum, Mixogen [Injection])
- Estradiol benzoate/testosterone isobutyrate (Femandren M, Folivirin)
- Estradiol butyrylacetate/testosterone ketolaurate/reserpine (Klimanosid R-Depot)
- Estradiol cypionate/testosterone cypionate (Depo-Testadiol, Femovirin)
- Estradiol cypionate/testosterone enanthate (Supligol)
- Estradiol valerate/prasterone enanthate (Binodian Depot, Cidodian Depot, Gynodian Depot, Klimax, Supligol NF)
- Estradiol valerate/testosterone enanthate (Deladumone, Despamen, Ditate, Ditate-DS, Gravignost, Primodian Depot, Valertest)
Veterinary
[edit]Marketed
[edit]- Diethylstilbestrol/methyltestosterone (Maxymin, Tylosterone)
- Diethylstilbestrol/testosterone (Rapigain)
- Estradiol benzoate/estradiol enanthate/testosterone enanthate (Uni-Bol)
- Estradiol benzoate/testosterone propionate (Component E-H, Implix BF, Progro H, Synovex H)
- Ethinylestradiol/methyltestosterone (Taril)
Estrogens and progestogens
[edit]Oral
[edit]Marketed
[edit]- Drospirenone/estetrol (Nextstellis, Drovelis, Lydisilka)
- Estradiol/nomegestrol acetate (Naemis, Zoely)
- Estradiol valerate/cyproterone acetate (Femilar)
- Estradiol valerate/dienogest (Natazia, Qlaira)
- Ethinylestradiol/chlormadinone acetate (Belara)[3]
- Ethinylestradiol/cyproterone acetate (Diane, Diane-35)
- Ethinylestradiol/desogestrel (Alenvona, Apri,[4] Azurette,[5] Bekyree,[6] Bimizza,[7] Caziant,[8] Cesia,[9] Cimizt,[10] Cyclessa,[11] Cyred,[12] Denise, Desogen,[13] Desirett, Emoquette,[14] Enskyce,[15] Gedarel, Gracial, Isibloom,[16] Juleber,[17] Kalliga, Kariva,[18] Kimidess,[19] Laurina, Linessa, Marvelon,[20][21][22] Mercilon,[23][24] Mircette,[25] Mirvala, Novynette, Ortho-Cept,[26] Pimtrea,[27] Reclipsen,[28] Regulon, Simliya,[29] Solia, Velivet,[30] Viorele,[31] Volnea[32])
- Ethinylestradiol/dienogest (Valette)
- Ethinylestradiol/dimethisterone (Oracon)
- Ethinylestradiol/drospirenone (Yasmin, Yasminelle, Yaz)
- Ethinylestradiol/drospirenone/levomefolic acid (Beyaz, Safyral)
- Ethinylestradiol/etynodiol diacetate (Demulen)
- Ethinylestradiol/gestodene (Femodene, Femodette, Gynera, Harmonet, Meliane, Minesse, Minulet)
- Ethinylestradiol/levonorgestrel (Amethyst, Aviane, Balcoltra, Falmina, Levlen, Lillow, Orsythia, Vienva)
- Ethinylestradiol/levonorgestrel/bisglycinate
- Ethinylestradiol/levonorgestrel/ferrous fumarate
- Ethinylestradiol/lynestrenol (Lyndiol)
- Ethinylestradiol/medroxyprogesterone acetate (Gianda, Provest)
- Ethinylestradiol/megestrol acetate (Nuvacon, Volidan)
- Ethinylestradiol/norethisterone (Brevicon, Norinyl 1+35, Ortho-Novum 7/7/7, Taytulla, Tri-Norinyl, Zenchent)
- Ethinylestradiol/norethisterone/ferrous fumarate (Blisovi 24 FE, Estrostep Fe, Femcon FE, Kaitlib FE, Lo Minastrin Fe, Loestrin 24 Fe, Microgestin 24 FE)
- Ethinylestradiol/norethisterone acetate (FemHRT)
- Ethinylestradiol/norethisterone acetate/ferrous fumarate
- Ethinylestradiol/norgestimate (Ortho Tri-Cyclen, Sprintec)
- Ethinylestradiol/norgestrel (Ovral)
- Ethinylestradiol/norgestrienone (Miniplanor, Planor)
- Ethinylestradiol/quingestanol acetate (Riglovis)
- Ethinylestradiol sulfonate/norethisterone acetate (Deposiston)
- Mestranol/anagestone acetate (Neo-Novum)
- Mestranol/chlormadinone acetate (C-Quens, Lutedion)
- Mestranol/etynodiol diacetate (Ovulen)
- Mestranol/hydroxyprogesterone acetate (Hormolidin)
- Mestranol/lynestrenol (Lyndiol)
- Mestranol/norethisterone (Norethin, Noriday, Norinyl, Norquen, Ortho-Novum)
- Mestranol/noretynodrel (Enavid, Enovid)
- Quinestrol/etynodiol diacetate (Soluna)
- Quinestrol/levonorgestrel (Yuèkětíng, Àiyuè)
- Quinestrol/norgestrel (Compound Norgestrel)
- Quinestrol/quingestanol acetate (Unovis)
For menopausal hormone therapy and/or gynecological disorders:
- Conjugated estrogens/medrogestone (Presomen)
- Conjugated estrogens/medroxyprogesterone acetate (Prempro, Premphase)
- Conjugated estrogens/norgestrel (Prempak-C)
- Estradiol/drospirenone (Angeliq)
- Estradiol/dydrogesterone (Femoston)
- Estradiol/gestodene (Avaden, Avadene)
- Estradiol/levonorgestrel
- Estradiol/medroxyprogesterone acetate (Indivina, Tridestra)
- Estradiol/norethisterone acetate (Activella, Activelle, Cliane, Estalis, Eviana, Evorel, Kliogest, Novofem)
- Estradiol/norgestimate (Prefest)
- Estradiol/progesterone (Bijuva)
- Estradiol/trimegestone (Lovelle, Totelle)
- Estradiol valerate/cyproterone acetate (Climen, Climen 28)
- Estradiol valerate/estriol/levonorgestrel (CycloÖstrogynal)
- Estradiol valerate/levonorgestrel (Cyclo-Progynova N)
- Estradiol valerate/medroxyprogesterone acetate (Dilena, Divina, Divitren, Farludiol, Indivina, Sisare)
- Estradiol valerate/norethisterone (Climagest, Climesse)
- Estradiol valerate/norethisterone acetate (Cliovelle, Norestin, Trisequens)
- Estradiol valerate/norgestrel (Cyclacur, Cyclocur, Cyclo-Progynova, Postoval, Progyluton)
- Ethinylestradiol/ethisterone (Amenorone, Di-Pro, Duosterone, Menstrogen, Oracecron, Orasecron)[2][1]
- Mestranol/noretynodrel (Enovid)
Never or not yet marketed
[edit]- Estradiol/norethisterone (Netagen, Netagen 403)
Transdermal
[edit]Marketed
[edit]- Ethinylestradiol/norelgestromin (Evra, Ortho Evra, Xulane)
For menopausal hormone therapy:
- Estradiol/levonorgestrel (Climara Pro)
- Estradiol/norethisterone acetate (CombiPatch)
Vaginal
[edit]Marketed
[edit]In contraceptive vaginal rings:
- Ethinylestradiol/etonogestrel (Circlet, NuvaRing)
- Segesterone acetate/ethinylestradiol (Annovera)
Injection
[edit]Marketed
[edit]In combined injectable contraceptives:
- Estradiol/megestrol acetate (Mego-E, Chinese Injectable No. 2)
- Estradiol benzoate/estradiol valerate/hydroxyprogesterone caproate (Sin-Ol)
- Estradiol benzoate butyrate/algestone acetophenide (Redimen, Soluna, Unijab)
- Estradiol cypionate/hydroxyprogesterone caproate (Sinbios)
- Estradiol cypionate/medroxyprogesterone acetate (Cyclo-Provera, Cyclofem, Lunelle)
- Estradiol enanthate/algestone acetophenide (Anafertin, Deladroxate, Perlutan, Topasel, Yectames)
- Estradiol valerate/hydroxyprogesterone caproate (Chinese Injectable No. 1)
- Estradiol valerate/norethisterone enanthate (Mesigyna, Mesygest)
For menopausal hormone therapy, gynecological disorders, habitual abortion, and other indications:
- Estradiol/progesterone (Juvenum)
- Estradiol benzoate/hydroxyprogesterone caproate (Primosiston)
- Estradiol benzoate/progesterone (Duogynon, Sistocyclin)
- Estradiol dipropionate/hydroxyprogesterone caproate (EP Hormone Depot)
- Estradiol hemisuccinate/progesterone (Hosterona)
- Estradiol pivalate/progesterone (Estrotate with Progesterone)
- Estradiol valerate/hydroxyprogesterone caproate (Gravibinan, Gravibinon)
- Estrone/progesterone (Synergon)
Never marketed
[edit]In combined injectable contraceptives:
- Estradiol/progesterone (in microspheres and macrocrystalline aqueous suspension)
- Estradiol undecylate/norethisterone enanthate
- Estradiol valerate/megestrol acetate
- Estradiol valerate/methenmadinone caproate (Lutofollin)
- Polyestradiol phosphate/medroxyprogesterone acetate
- Additional preparations listed at Combined injectable birth control § Research
For other indications:
- Estradiol valerate/gestonorone caproate (SH-834, SH-8.0834)
Veterinary
[edit]Marketed
[edit]- Estradiol benzoate/progesterone (Component E-S, Implix BM, Synovex C, Synovex S)
- Estradiol valerate/norgestomet (Syncro-Mate-B)
Androgens and progestogens
[edit]Oral
[edit]Marketed
[edit]- Methyltestosterone/ethisterone (Androgeston)[1]
Injection
[edit]Marketed
[edit]Veterinary
[edit]Marketed
[edit]- Danazol/megestrol acetate (Dogalact)
- Nandrolone decanoate/methandriol dipropionate (Filybol, Tribolin)
- Nandrolone phenylpropionate/methandriol dipropionate (RWR)
Estrogens, progestogens, and androgens
[edit]Oral
[edit]Marketed
[edit]- Methylestradiol/normethandrone (Ginecosid, Ginecoside, Mediol, Renodiol)
Not yet marketed
[edit]Sublingual
[edit]Marketed
[edit]- Estradiol/progesterone/methyltestosterone (Trihormonal)[1]
- Ethinylestradiol/ethisterone/methyltestosterone (Trinestryl, Trimone Sublets)[1]
Injection
[edit]Marketed
[edit]- Estradiol benzoate/progesterone/methandriol dipropionate (Progestandron)
- Estradiol benzoate/progesterone/testosterone propionate (Lukestra, Steratrin, Trihormonal, Trinestryl)[1][2][36]
- Estradiol benzoate/estradiol valerate/norethisterone acetate/testosterone enanthate (Ablacton)
- Estradiol dibutyrate/hydroxyprogesterone heptanoate/testosterone caproate (Triormon Depositum)
- Estradiol diundecylate/hydroxyprogesterone heptanoate/testosterone cyclohexylpropionate (Trioestrine Retard)
- Estradiol hexahydrobenzoate/hydroxyprogesterone caproate/testosterone hexahydrobenzoate (Trinestril AP)
- Estrone/progesterone/testosterone (Tristeron, Tristerone)[36]
Never marketed
[edit]- Estrapronicate/hydroxyprogesterone heptanoate/nandrolone undecanoate (Trophobolene, Trophoboline)
Veterinary
[edit]Marketed
[edit]- Estradiol/trenbolone acetate (Component, Compudose-G, Progro TE-H, Revalor, Synovex)
- Estradiol benzoate/trenbolone acetate (Synovex Choice, Synovex One, Synovex Plus, Synovex with Trenbolone Acetate)
Miscellaneous
[edit]Oral
[edit]Marketed
[edit]- Conjugated estrogens/bazedoxifene (Duavee)
Never marketed
[edit]Transdermal
[edit]Marketed
[edit]- Estradiol benzoate/prednisolone/salicylic acid (Alpicort E, Alpicort F, Alpicort Plus)
Vaginal
[edit]Marketed
[edit]- Estradiol benzoate/gentamicin/hydrocortisone/nystatin (Cridermol Fem, Ginabiot, Ginecovan)
- Estradiol benzoate/monalazone (Malun-25)
Mixed
[edit]Marketed
[edit]- Goserelin/bicalutamide (ZolaCos CP)
- Leuprorelin/norethisterone acetate (Lupaneta Pack)
See also
[edit]References
[edit]- ^ a b c d e f g h i j Hans Hermann Julius Hager; Walther Kern; Paul Heinz List; Hermann Josef Roth (29 July 2013). Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Ärzte und Medizinalbeamte: Wirkstoffgruppen II Chemikalien und Drogen (A-AL). Springer-Verlag. pp. 143, 185–187. ISBN 978-3-662-25655-8. Archived from the original on 6 September 2022. Retrieved 3 June 2019.
- ^ a b c d e Georg Arends; Heinrich Zörnig; Hermann Hager; Georg Frerichs, Walther Kern (14 December 2013). Hagers Handbuch der pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Drogisten, Ärzte u. Medizinalbeamte. Springer-Verlag. pp. 1163–1164. ISBN 978-3-662-36329-4. Archived from the original on 6 September 2022. Retrieved 3 June 2019.
- ^ "Archived copy" (PDF). Archived (PDF) from the original on 2022-09-06. Retrieved 2022-09-06.
{{cite web}}: CS1 maint: archived copy as title (link) - ^ "Apri 28 Day- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 10 July 2021. Retrieved 10 July 2021.
- ^ "Azurette- desogestrel/ethinyl estradiol and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Bekyree- desogestrel and ethinyl estradiol and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Bimizza 150 microgram/20 microgram Tablets - Summary of Product Characteristics (SmPC)". (emc). Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Caziant Triphasic Regimen- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Cesia- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Cimizt 150 microgram/30 microgram Tablets - Summary of Product Characteristics (SmPC)". (emc). Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Cyclessa Tablets (desogestrel and ethinyl estradiol tablets USP)". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Cyred EQ- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Desogen Tablets". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Emoquette- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Enskyce- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Isibloom- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Juleber- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Kariva- desogestrel/ethinyl estradiol and ethinyl estradiol kit". DailyMed. Archived from the original on 10 July 2021. Retrieved 10 July 2021.
- ^ "Kimidess (Desogestrel and Ethinyl Estradiol Tablets, USP and Ethinyl Estradiol Tablets, USP), 0.15 mg/0.02 mg and 0.01 mg". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Marvelon Tablets - Summary of Product Characteristics (SmPC)". (emc). Archived from the original on 10 July 2021. Retrieved 10 July 2021.
- ^ "Marvelon desogestrel / ethinylestradiol 28 tablets". Therapeutic Goods Administration (TGA). Archived from the original on 2021-07-11. Retrieved 2021-07-11.
- ^ "Marvelon Product Information". Therapeutic Goods Administration (TGA). Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Mercilon- desogestrel, ethinyl estradiol tablet". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Mercilon Tablets - Summary of Product Characteristics (SmPC)". (emc). Archived from the original on 10 July 2021. Retrieved 10 July 2021.
- ^ "Mircette- desogestrel/ethinyl estradiol and ethinyl estradiol kit". DailyMed. Archived from the original on 10 July 2021. Retrieved 10 July 2021.
- ^ "Ortho-Cept Tablets (Desogestrel And Ethinyl Estradiol)". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Pimtrea- desogestrel/ethinyl estradiol and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Reclipsen 28 Day- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Simliya- desogestrel and ethinyl estradiol and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Velivet Triphasic Regimen- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 10 July 2021. Retrieved 10 July 2021.
- ^ "Viorele- desogestrel and ethinyl estradiol and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ "Volnea- desogestrel and ethinyl estradiol kit". DailyMed. Archived from the original on 11 July 2021. Retrieved 10 July 2021.
- ^ Josef Kimmig (14 March 2013). Therapie der Haut- und Geschlechtskrankheiten. Springer-Verlag. pp. 508–. ISBN 978-3-642-94850-3. Archived from the original on 29 August 2021. Retrieved 3 June 2019.
- ^ "Spezialitäten". Klinische Wochenschrift. 30 (15–16): 367. 1952. doi:10.1007/BF01472052. ISSN 0023-2173. S2CID 264011779.
- ^ Archived copy Archived 2019-06-09 at the Wayback Machine
- ^ a b Hormone und Psyche die Endokrinologie des Alternden Menschen: Fünftes Symposion der Deutschen Gesellschaft für Endokrinologie Freiburg (Breisgau), den 7. bis 9. März 1957. Springer-Verlag. 9 March 2013. pp. 55–. ISBN 978-3-642-87014-9. Archived from the original on 7 April 2022. Retrieved 9 June 2019.
