Moscow State University (MSU), officially M. V. Lomonosov Moscow State University, is a public research university in Moscow, Russia. The university includes 15 research institutes, 43 faculties, more than 300 departments, and six branches. Alumni of the university include past leaders of the Soviet Union and other governments. As of 2019, 13 Nobel laureates, six Fields Medal winners, and one Turing Award winner were affiliated with the university.

Ivan Shuvalov and Mikhail Lomonosov promoted the idea of a university in Moscow, and Russian Empress Elizabeth decreed its establishment on 23 January [O.S. 12 January] 1755.

The first lectures were given on 7 May [O.S. 26 April]. Saint Petersburg State University and MSU each claim to be Russia's oldest university. Though Moscow State University was founded in 1755, St. Petersburg which has had a continuous existence as a "university" since 1819 sees itself as the successor of an academy established on in 1724, by a decree of Peter the Great.^{[citation needed]}

MSU originally occupied the Principal Medicine Store on Red Square from 1755 to 1787. Catherine the Great transferred the university to a building on the other side of Mokhovaya Street, constructed between 1782 and 1793, to a design by Matvei Kazakov, and rebuilt by Domenico Giliardi after fire consumed much of Moscow in 1812.^{[citation needed]}

In the 18th century, the university had three departments: philosophy, medicine, and law. A preparatory college was affiliated with the university until its abolition in 1812. In 1779, Mikhail Kheraskov founded a boarding school for noblemen (Благородный пансион) which in 1830 became a gymnasium for Russian nobility. The university press, run by Nikolay Novikov in the 1780s, published the newspaper in Imperial Russia: Moskovskie Vedomosti.^{[citation needed]}

In 1804, medical education split into clinical (therapy), surgical, and obstetrics faculties. Between 1884 and 1897, the Department of Medicine built a medical campus in Devichye Pole, between the Garden Ring and Novodevichy Convent; designed by Konstantin Bykovsky ^[ru], with university doctors like Nikolay Sklifosovskiy and Fyodor Erismann acting as consultants. The campus, and medical education in general, were separated from Moscow University in 1930. Devichye Pole was operated by the independent I.M. Sechenov First Moscow State Medical University and by various other state and private institutions.^{[citation needed]}

The roots of student unrest in the university reach deep into the nineteenth century. In 1905, a social-democratic organization emerged at the university and called for the overthrow of the Czarist government and the establishment of a republic in Russia. The imperial government repeatedly threatened to close the university. In 1911, in a protest over the introduction of troops onto the campus and mistreatment of certain professors, 130 scientists and professors resigned en masse, including Nikolay Dimitrievich Zelinskiy, Pyotr Nikolaevich Lebedev, and Sergei Alekseevich Chaplygin; thousands of students were expelled.^{[citation needed]}

After the October Revolution of 1917, the institution began to admit children of the proletariat and peasantry. In 1919, the university abolished tuition fees, and established a preparatory facility to help working-class children prepare for entrance examinations. During the implementation of Joseph Stalin's first five-year plan (1928–32), the university was expanded.^{[citation needed]}