For most of its history, Qatar practiced slavery until its abolition in 1952. Many members of the Afro-Arabian minority are descendants of the former slaves. Chattel slavery was succeeded by the Kafala system. The kafala system has been abolished in Qatar since December 2016. However, concerns still remain about workers' rights and employers retaining considerable power over workers.

During the Omani Empire (1692–1856), Oman was a center of the Zanzibar slave trade. Slaves were trafficked from the Swahili coast of East Africa via Zanzibar to Oman. From Oman, the slaves were exported to the rest of the Arabian Peninsula and Persia, including the Trucial States, Qatar, Bahrain and Kuwait. Oman's optimal location between the Arabian Sea and the Gulf region positioned it as a key player in the Zanzibar slave trade. Serving as a pivotal navigation point, Oman gained significant importance in the history of the Arabian Gulf region. The economic impact of the slave trade persisted, becoming a substantial factor in shaping Oman's economy in the post-slave trade era.

The Omani slave trade from Africa started to shrink in the late 19th century.

A second route of slave trade existed, with people from both Africa and East Asia, who were smuggled to Jeddah in the Arabian Peninsula in connection to the Muslim pilgrimage, Hajj, to Mecca and Medina. Victims were tricked to perform the journey willingly in the belief that they were going on the Hajj pilgrimage, or employed as servants, and then sold upon arrival. These slaves were then exported from the Hejaz to Oman, the Trucial States, Qatar, Bahrain and Kuwait.

In the 1940s, a third slave trade route was noted, in which Balochis from Balochistan were shipped across the Persian Gulf, many of whom had sold themselves or their children to escape poverty. In 1943, it was reported that Baloch girls were shipped via Oman and the Trucial States to Mecca, where they were popular as concubines (sex slaves), since Caucasian girls were no longer available, and were sold for $350–450.

Slavery was practiced by the House of Thani and the wealthy merchants, but also by ordinary villagers, who could own only one or two slaves.

Female slaves were primarily used as either domestic servants, or as concubines (sex slaves). The PDQ Oil Company had 250 slave laborers during its first year of production in Qatar in 1949.

Black African women were primarily used as domestic house slaves rather than exclusively for sexual services, while white Caucasian women (normally Circassian or Georgian) were preferred as concubines (sex slaves), and when the main slave route of white slave girls was reduced after Russia's conquest of the Caucasus and Central Asia in the mid 19th-century (reducing the Black Sea slave trade and the Kazakh Khanate slave trade), Baluchi and "Red" Ethiopian (Oromo and Sidamo) women became the preferred targets for sexual slavery. Non-African female slaves were sold in the Persian Gulf where they were bought for marriage; these were fewer and often Armenian, Georgian, or from Baluchistan and India.