Tehran Museum of Contemporary Art (Persian: موزه هنرهای معاصر تهران), also known as TMoCA, is among the largest art museums in Tehran and Iran. It has collections of more than 3,000 items that include 19th and 20th-century's world-class European and American paintings, prints, drawings, and sculptures. TMoCA also has one of the greatest collections of Iranian modern and contemporary art.

The museum was inaugurated by Shahbanu Farah Pahlavi (Persian: فرح پهلوی) in 1977, just two years before the 1979 Revolution. TMoCA is considered to have the most valuable collections of modern Western masterpieces outside Europe and North America.

According to Shahbanu Farah, the idea for the museum originated in a conversation at a gallery opening in the 1970s, when the artist Iran Darroudi mentioned her desire for a permanent place to exhibit works. The Tehran Museum of Contemporary Art was supposed to be a place to show contemporary and modern Iranian artists alongside other international artists doing similar work.

The museum was designed by Iranian architect and cousin of the empress, Kamran Diba, who employed elements from traditional Persian architecture of Yazd, Kashan, and other desert towns. Diba collaborated with architect Nader Ardalan during the design phase. It was built adjacent to Farah Park, renamed Laleh Park after the Islamic revolution, and was inaugurated in 1977. The building itself can be regarded as an example of contemporary art, in a style of an underground New York Guggenheim Museum. Most of the museum area is located underground with a circular walkway that spirals downwards with galleries branching outwards. Western sculptures by artists such as Ernst, Giacometti, Magritte, and Moore can be found in the museum's gardens.

The art selection was done under the office of Shahbanu Farah with a budget from the National Iranian Oil Company. The Shahbanu personally met many of the artists whose work was part of the museum collection, including the Western artists Marc Chagall, Salvador Dalí, Henry Moore, Paul Jenkins, Arnaldo Pomodoro. Some people involved in the process of selecting art were the Americans, Donna Stein and David Galloway, and Kamran Diba, the architect and director of the museum, and Karimpasha Bahadori, who was the Chief of Staff of the cabinet.

After the Iranian Revolution in 1979, the Western art was stored away in the museum's vault until 1999 when the first post-revolution exhibition was held of western art showing artists such as David Hockney, Roy Lichtenstein, Robert Rauschenberg and Andy Warhol. Now pieces of the Western art collection are shown for a few weeks every year but due to the current conservative nature of the Iranian establishment, most pieces are never be shown.

It is considered to have the most valuable collection of Western modern art outside Europe and the United States, a collection largely assembled by founding curators David Galloway and Donna Stein under the patronage of Farah Pahlavi. It is said that there is approximately £2.5 billion worth of modern art held at the museum. The museum hosts a revolving program of exhibitions and occasionally organizes exhibitions by local artists.

Collection curator Donna Stein later wrote a memoir, The Empress and I: How an Ancient Empire Collected, Rejected and Rediscovered Modern Art (2021), because she felt she was not properly credited for her role in curating this collection.