Telescopium is a minor constellation in the southern celestial hemisphere, one of twelve named in the 18th century by French astronomer Nicolas-Louis de Lacaille and one of several depicting scientific instruments. Its name is a Latinized form of the Greek word for telescope. Telescopium was later much reduced in size by Francis Baily and Benjamin Gould.

The brightest star in the constellation is Alpha Telescopii, a blue-white subgiant with an apparent magnitude of 3.5, followed by the orange giant star Zeta Telescopii at magnitude 4.1. Eta and PZ Telescopii are two young star systems with debris disks and brown dwarf companions. Telescopium hosts two unusual stars with very little hydrogen that are likely to be the result of two merged white dwarfs: PV Telescopii, also known as HD 168476, is a hot blue extreme helium star, while RS Telescopii is an R Coronae Borealis variable. RR Telescopii is a cataclysmic variable that brightened as a nova to magnitude 6 in 1948.

It had been hypothesized in 2020 that Telescopium would also host the first known visible star system with a black hole, QV Telescopii (HR 6819), however observations in 2022 indicated that this is a binary system of two main-sequence stars without a black hole instead.

Telescopium was introduced in 1751–52 by Nicolas-Louis de Lacaille with the French name le Telescope, depicting an aerial telescope, after he had observed and catalogued 10,000 southern stars during a two-year stay at the Cape of Good Hope. He devised 14 new constellations in uncharted regions of the Southern Celestial Hemisphere not visible from Europe. All but one honored instruments that symbolised the Age of Enlightenment. Covering 40 degrees of the night sky, the telescope stretched out northwards between Sagittarius and Scorpius. Lacaille had Latinised its name to Telescopium by 1763.

The constellation was known by other names. It was called Tubus Astronomicus in the eighteenth century, during which time three constellations depicting telescopes were recognised—Tubus Herschelii Major between Gemini and Auriga and Tubus Herschelii Minor between Taurus and Orion, both of which had fallen out of use by the nineteenth century. Johann Bode called it the Astronomische Fernrohr in his 1805 Gestirne and kept its size, but later astronomers Francis Baily and Benjamin Gould subsequently shrank its boundaries. The much-reduced constellation lost several brighter stars to neighbouring constellations: Beta Telescopii became Eta Sagittarii, which it had been before Lacaille placed it in Telescopium, Gamma was placed in Scorpius and renamed G Scorpii by Gould, Theta Telescopii reverted to its old appellation of d Ophiuchi, and Sigma Telescopii was placed in Corona Australis. Initially uncatalogued, the latter is now known as HR 6875. The original object Lacaille had named Eta Telescopii—the open cluster Messier 7—was in what is now Scorpius, and Gould used the Bayer designation for a magnitude 5 star, which he felt warranted a letter.

A small constellation, Telescopium is bordered by Sagittarius and Corona Australis to the north, Ara to the west, Pavo to the south, and Indus to the east, cornering on Microscopium to the northeast. The three-letter abbreviation for the constellation, as adopted by the International Astronomical Union in 1922, is "Tel". The official constellation boundaries, as set by Belgian astronomer Eugène Delporte in 1930, are defined by a quadrilateral. In the equatorial coordinate system, the right ascension coordinates of these borders lie between 18^h 09.1^m and 20^h 29.5^m , while the declination coordinates are between −45.09° and −56.98°. The whole constellation is visible to observers south of latitude 33°N.

Within the constellation's borders, there are 57 stars brighter than or equal to apparent magnitude 6.5. With a magnitude of 3.5, Alpha Telescopii is the brightest star in the constellation. It is a blue-white subgiant of spectral type B3IV which lies around 250 light-years away. It is radiating nearly 800 times the Sun's luminosity, and is estimated to be 5.2±0.4 times as massive and have 3.3±0.5 times the Sun's radius. Close by Alpha Telescopii are the two blue-white stars sharing the designation of Delta Telescopii. Delta¹ Telescopii is of spectral type B6IV and apparent magnitude 4.9, while Delta² Telescopii is of spectral type B3III and magnitude 5.1. They form an optical double, as the stars are estimated to be around 710 and 1190 light-years away respectively. The faint (magnitude 12.23) Gliese 754, a red dwarf of spectral type M4.5V, is one of the nearest 100 stars to Earth at 19.3 light-years distant. Its eccentric orbit around the Galaxy indicates that it may have originated in the Milky Way's thick disk.

At least four of the fifteen stars visible to the unaided eye are orange giants of spectral class K. The second brightest star in the constellation—at apparent magnitude 4.1—is Zeta Telescopii, an orange subgiant of spectral type K1III-IV. Around 1.53 times as massive as the Sun, it shines with 512 times its luminosity. Located 127 light years away from Earth, it has been described as yellow or reddish in appearance. Epsilon Telescopii is a binary star system: the brighter component, Epsilon Telescopii A, is an orange giant of spectral type K0III with an apparent magnitude of +4.52, while the 13th magnitude companion, Epsilon Telescopii B, is 21 arcseconds away from the primary, and just visible with a 15 cm aperture telescope on a dark night. The system is 417 light-years away. Iota Telescopii and HD 169405—magnitude 5 orange giants of spectral types K0III and K0.5III respectively—make up the quartet. They are around 370 and 497 light-years away from the Sun respectively. Another ageing star, Kappa Telescopii is a yellow giant with a spectral type G9III and apparent magnitude of 5.18. Around 1.87 billion years old, this star of around 1.6 solar masses has swollen to 11 times the Sun's diameter. It is approximately 293 light-years from Earth, and is another optical double.