The tribe Tragelaphini (referred to by some authors as "Strepsicerotini"), or the spiral-horned antelopes, are bovines that are endemic to sub-Saharan Africa. These include the bushbucks, kudus, and the elands. The scientific name is in reference to the mythical creature the tragelaph, a Chimera with the body of a stag and the head of a goat. They are medium-to-large, tall, long-legged antelopes characterized by their iconic twisted horns and striking pelage coloration patterns (most common is the distinctive white, vertical barring).

Despite being among the largest species of antelope, they are actually more closely related to cattle (Bos taurus), and together along with a few apparent Asiatic species belong to the subfamily Bovinae. While the group's evolutionary history occurred in Africa, there have been fossil species that have been found in Eurasia (which may also be the place of origin for this group). The number of genera and species is debated as some consider there to be one or two genera with nine species, while others consider there to be five genera and 25 species. In general, spiral-horned antelopes can be roughly divided into two groups: robust forms (which only consists of the two eland species, Taurotragus) and gracile forms (the rest of them, in the genus Tragelaphus, although this taxon is an unnatural grouping, and might warrant additional genera).

Spiral-horned antelopes are browsers, found in a wide variety of environments both arid and humid, including semi-deserts, savannas, rainforests and mountains. In all these environments, however, they prefer to live in dense bush or thicket, which offer concealment from their natural predators. Considered among the most beautiful and charismatic bovids, the various species of spiral-horned antelopes are popular in zoos and game reserves. The two eland species have been ranched as alternatives to cattle, being hardy in extreme environments, relatively placid in character, and nutritionally superior as a meat source.

The tribe name "Tragelaphini" was published as a subfamily ("Tragelaphinae") by British zoologist Edward Blyth in 1863, and was downgraded to tribe by Russian zoologist Vladimir Sokolov in 1953. It refers to the mythical tragelaph which was imagined to be half-goat, half-stag. The root words come from Greek, with τράγος (trágos) meaning "male goat" and έλαφος (élaphos) meaning "stag". The suffix "–ini" refers to their ranking as a tribe.

The alternative name "Strepsicerotini" was published by another British zoologist John Edward Gray as "Strepsiceriae" earlier in 1846. It comes from Greek with στρεπτός (streptós) meaning "twisted" and κέρατος (kératos) meaning "horn", referring to the shape of this group's horns. However, "Strepsiceriae" had the incorrect prefix and suffix, which this was corrected to "Strepsicerotini" in 1945 by American paleontologist George Gaylord Simpson. While the name "Strepsicerotini" was published first, most scientists used the latter name "Tragelaphini" as it is more widely used.

The spiral-horned antelopes belong to the subfamily Bovinae which also includes oxen of the tribe Bovini and two aberrant species of Asian antelope, the four-horned antelope and the nilgai which belong to the tribe Boselaphini. The relationship between the tribes varies in research concerning their phylogeny. Most molecular research supports a Bovini and Tragelaphini subclade of Bovinae. There are also some morphological support for oxen being the closet living relatives to the spiral-horned antelopes, most notably both groups have horn cores with a pedicle (the attachment point to the skull).

There has been a few studies which have supported alternate arrangements, one being a sister relationship between the nilgai (Boselaphus tragocamelus) and the spiral-horned antelopes. Historically, the nilgai was classified as a tragelaphine by some scientists. Benirschke et al. (1980) worked on karyotypes with the lesser kudu and found them to share with the nilgai an X chromosome fused with autosome 14. Another study that analyzed the COII gene found the nilgai and lesser kudu being sister species (although the support was low and had limited species sampling). The majority of other molecular and morphological work do not support the placement of the nilgai in Tragelaphini, as it contradicts with their data and results.

Tragelaphini has diverged from their closet sister taxon for the last 15 to 18 million years. It was once thought that spiral-horned antelopes were uniquely African, but there have been Eurasian fossils found in Greece and the Caucasus. Kostopoulos and Koufos (2006) have described Pheraios chryssomallos from fossils found in the Turolian locality of Thessaly, Greece. The authors have found cladistic support of P. chryssomallos being the basal most tragelaphin (or at least a sister taxon to the group) based on 46 cranial features. This suggests that the ancestor of all known species of spiral-horned antelope must have originated in Europe during the late Miocene. The eastern European genus Pontoceros is another example, although this animal has been found in early Pleistocene beds of the Mygdonia basin. This suggests that spiral-horned antelopes have emigrated from Africa and into Eurasia during a latter period in their evolutionary history. In addition, undescribed fossils found in South Asia could be related to spiral-horned antelopes.