Vis (pronounced [ʋi:s]) is a Croatian island in the Adriatic Sea. Before the end of World War I, the island was held by the Liburnians, the Republic of Venice, the Napoleonic Kingdom of Italy, and the Austrian Empire. During the 19th century, the sea to the north of Vis was the site of two naval battles. In 1920, the island was ceded to the Kingdom of Yugoslavia as part of the Treaty of Rapallo. During World War II, the island was the headquarters of the Yugoslav Partisan movement. After the war, Vis was used as a naval base for the Yugoslav People's Army until 1989. The island's main industries are viticulture, fishing, fish processing, and tourism.

The farthest inhabited island off the Croatian mainland, Vis had a population of 3,313 in 2021. Vis has an area of 90.26 square kilometres (34.85 square miles). Its highest point is Hum, which is 587 metres (1,926 feet) above sea level. The island's two largest settlements are the town of Vis on the island's eastern side (the settlement for which the island was originally named) and Komiža on its western coast.

Vis, along with Brusnik, Sveti Andrija and the neighbouring islet of Kamnik, Biševo, Jabuka and the Palagruža archipelago, forms part of the Croatian Offshore Islands Important Bird Area (IBA). This was designated as such by BirdLife International because it supports significant breeding populations of Scopoli's and Yelkouan shearwaters, as well as of Eleonora's falcons.

Vis was inhabited by the time of the Neolithic period. In the 4th century BC, the Greek tyrant of Syracuse, Dionysius the Elder, founded the colony Issa (Ancient Greek: Ἴσσα) on the island. A town on an island of the same name was settled by Illyrians, who were under the domination of Liburni from the 8th to the 6th centuries B.C. At the beginning of the 4th century B.C. the island was colonized by Syracusan Greeks as part of a plan of Dionysios the Elder to control the Adriatic.

During the 3rd century Issa founded the emporia Tragurion (Traù, now Trogir) and Epetion (Stobreč) on the Illyrian mainland. Its predominance in the region lasted until the first Illyro-Roman war 229-219 B.C. when it became a pawn in the battles of greater powers. In the civil war it sided with Pompey and consequently lost its privileges and autonomy in 47 B.C. when it was reduced to the rank of an oppidum civium Romanorum and was dependent on the newly founded colony at Salona. As a polis, Issa minted its own money, and these coins of many types had wide circulation. The town, situated on a slope on the W side of a large bay, was defended by strong Hellenistic walls, still visible in an irregular quadrangle (265 x 360 m) that enclosed an area of 9.8 ha. The street grid and foundations of houses have been found.

The necropolis has yielded many pieces of pottery, including some from South Italy. The wall of the cavea of the theater, built in the Roman period, is incorporated into the present Franciscan Monastery. It could seat about 3000 persons. Inscriptions, statues, coins, and pottery are preserved in the archaeological museums at Split and Zagreb. Later, it became an independent polis, and even minted its own money and founded its own colonies, the most notable of which was Aspálathos (the modern-day city of Split).

In the 1st century BC, the island was held by the Liburnians.

Until 1797, the island was under the rule of the Republic of Venice. During this time large settlements developed along the coastline (Comisa (now Komiža) and Lissa (now Vis)). Administratively, the island of Lissa was for centuries bound to the island of Lesina, now named Hvar. The Venetian influence is still recognizable in architecture found on the island.^{[citation needed]} The dialect of Croatian spoken on the island – called Cokavian – is recognized by the Croatian government as intangible cultural heritage and is notable for a large vocabulary of Venetian origin.