While raising a family and engaging in activism, Ames also pursued her interest in invention. She designed and patented several inventions aimed at improving household efficiency and convenience.

Ames developed an interest in architectural and mechanical design, creating innovative solutions for various practical problems. One of her most notable inventions was a device for notating musical compositions mechanically.

Ames secured several patents for her inventions, demonstrating the ingenuity and practicality of her designs. While not always commercially successful, her inventions showcased her creative spirit and problem-solving abilities.

Ames' work as an inventor served as an inspiration to other women interested in science and technology, demonstrating that women could excel in traditionally male-dominated fields.