DeShone Allen Kizer (/ˈkaɪzər/; born January 3, 1996) is an American former professional football quarterback who played in the National Football League (NFL) for four seasons. He played college football for the Notre Dame Fighting Irish and was selected by the Cleveland Browns in the second round of the 2017 NFL draft. Kizer served as the Browns' starter as a rookie, but his tenure lasted only one year after going winless and leading the league in interceptions. Kizer spent his last three seasons as a backup for the Green Bay Packers, Las Vegas Raiders, and Tennessee Titans.

Kizer attended Central Catholic High School in Toledo, Ohio. He was named the Associated Press Ohio Division III co-offensive player of the year as a senior in 2013. A three-year starter, Kizer helped lead the Fighting Irish high school football team to a combined 34–6 overall record in 2011–13 (8–2 in playoff games), including a 14–1 record and Ohio Division II state title in 2012.

In his career, Kizer's totals included 5,684 passing yards and 56 touchdowns to go with 1,211 rushing yards and 17 touchdowns.

Considered a four-star recruit by Rivals.com, Kizer was rated as the ninth best dual-threat quarterback prospect of his class. On June 11, 2013, Kizer announced his commitment to play college football at the University of Notre Dame for the Fighting Irish.

Kizer redshirted his first year at Notre Dame in 2014 behind quarterbacks Everett Golson and Malik Zaire.

Kizer started 2015 as a backup to Zaire. On September 5, during the season opener, Kizer made his collegiate debut against Texas in relief of Zaire in the 38–3 victory. During the second game of the season against Virginia, Kizer replaced an injured Zaire and helped lead Notre Dame to a victory. With 12 seconds left, Kizer completed a 39-yard touchdown pass to wide receiver Will Fuller to give Notre Dame the lead. After it was announced that Zaire would miss the rest of the season, Kizer was named the starter. On October 3, in a narrow 24–22 loss to Clemson, he passed for a season-high 321 yards, two touchdowns, and an interception while having 15 carries for 60 yards and a touchdown. On Halloween, in a 24–20 victory over Temple, Kizer recorded 299 passing yards, a touchdown, and two interceptions, and had a stellar night on the ground, rushing for 143 yards and two touchdowns. In the next game against Pitt, Kizer accounted for all six touchdowns (five passing and one rushing) helping Notre Dame to a 42–30 victory.

Kizer and the Fighting Irish finished the 2015 regular season with a 10–2 record. On New Year's Day, the Fighting Irish closed out their 2015 season with a 44–28 loss to Ohio State in the Fiesta Bowl. In the loss, Kizer had 284 passing yards, two touchdowns, and an interception to go along with 21 rushing yards and a touchdown. Overall, Kizer finished his redshirt first year with 2,880 passing yards, 525 rushing yards, and 31 total touchdowns in 13 games.

Kizer started the 2016 season with 215 passing yards, five passing touchdowns, 77 rushing yards, and a rushing touchdown in a double overtime 50–47 loss to Texas at Darrell K Royal–Texas Memorial Stadium. After a victory over Nevada, he had 344 passing yards and two touchdowns to go along with 14 rushing yards and two touchdowns in a 36–28 loss to Michigan State. After a loss to Duke, Kizer had a career day through the air with 471 yards and three touchdowns in a 50–33 victory over Syracuse. He put together some solid performances over the rest of the season, but the team faltered and ended up with a 4–8 record. Kizer played 12 games with 2,925 passing yards, 472 rushing yards, and 34 total touchdowns.