FAME (Florence Alabama Music Enterprises) Studios is a recording studio located at 603 East Avalon Avenue in Muscle Shoals, Alabama, United States, an area of northern Alabama known as the Shoals. Though small and distant from the main recording locations of the American music industry, FAME has produced many hit records and was instrumental in what came to be known as the Muscle Shoals sound. It was started in the 1950s by Rick Hall, known as the Founder of Muscle Shoals Music. The studio, owned by Linda Hall since 2018, is still actively operating. It was added to the Alabama Register of Landmarks and Heritage on December 15, 1997, and was listed on the National Register of Historic Places in 2016. The 2013 award-winning documentary Muscle Shoals features Rick Hall, the Muscle Shoals Rhythm Section (also called The Swampers), and the Muscle Shoals sound originally popularized by FAME.

In 1959, Rick Hall and Billy Sherrill accepted an offer from Tom Stafford, the owner of a recording studio, to help set up a new music publishing company in the town of Florence, Alabama, to be known as Florence Alabama Music Enterprises, or FAME. The studio was first located above Florence's City Drug Store. Two doors down was a pawn shop – "Uncle Sams" – where aspiring artists would buy or pawn their instruments, depending on the trajectory of their careers. The studio was moved to a former tobacco warehouse on Wilson Dam Road in Muscle Shoals in 1960, when Hall split from Sherrill and Stafford, leaving Hall with rights to the studio's name.

Hall soon recorded the first hit record from the Muscle Shoals area, Arthur Alexander's "You Better Move On" in 1961. Hall took the proceeds from that recording to build the current facility, on Avalon Avenue in Muscle Shoals. In 1963, he recorded the first hit produced in that building, Jimmy Hughes's "Steal Away".

FAME studio prospered, and by the late 1960s pop and soul musicians such as Otis Redding, Wilson Pickett, Clarence Carter, and Solomon Burke had recorded there. Singer Aretha Franklin credited Hall for the "turning point" in her career when she recorded at FAME in early 1967, taking her from a struggling artist to the "Queen of Soul". According to Hall, one of the reasons for FAME's success at a time of stiff competition from studios in other cities was that he overlooked the issue of race, a perspective he called "colorblind". "It was a dangerous time, but the studio was a safe haven where blacks and whites could work together in musical harmony," Hall wrote in his autobiography. Decades later, a publication in Malaysia referred to Hall as a "white fiddler who became an unlikely force in soul music".

As the word about Muscle Shoals began to spread other artists began coming there to record. The Nashville producer Felton Jarvis brought Tommy Roe and recorded Roe's song "Everybody" in 1963. The Atlanta music publisher Bill Lowery, who had mentored Hall in his early days, sent the Tams. The Nashville publisher and producer Buddy Killen brought Joe Tex. Leonard Chess encouraged Etta James to record there, and she made her 1967 hit "Tell Mama" and the Tell Mama album at FAME. Jerry Wexler of Atlantic Records brought both Wilson Pickett and Aretha Franklin to record. The recording session with Franklin brought unexpected conflict: one of the horn players sexually harassed the singer, and her husband had him fired from the session. Later that evening Hall went over to make up with Franklin and her husband, but a fight ensued, and the recording session was canceled. Wexler swore to Hall he would never work with him again.

Duane Allman, later of the Allman Brothers Band, pitched a tent and camped out in the parking lot of FAME Studios in 1968 in order to be near the recording sessions occurring there. He soon befriended Rick Hall and Wilson Pickett, who was recording there. While on lunch break, Allman taught Pickett "Hey Jude"; their version of the song was recorded with Allman playing lead guitar. On hearing the session, people at Atlantic began asking who had played the guitar solos, and Hall responded with a hand-written note that read "some hippie cat who's been living in our parking lot". Shortly afterward, Allman was offered a recording contract; auditions for the Allman Brothers Band were later held at FAME Studios. Allman loved the area, and frequently returned to the Shoals for session work throughout his short life.

The session musicians who worked at the studio became known as the Muscle Shoals Horns and the Muscle Shoals Rhythm Section (or the Swampers). In 1969, just after Hall had signed a deal with Capitol Records, the four primary Muscle Shoals Rhythm Section members (Barry Beckett (keyboards), Jimmy Johnson (guitar), Roger Hawkins (drums), and David Hood (bass), left to found a competing business, the Muscle Shoals Sound Studio, originally at 3614 Jackson Highway in nearby Sheffield, Alabama. Subsequently, Hall hired the Fame Gang as the new studio band. Also called the Third FAME Rhythm Section, consisted of eight musicians plus arranger-producer Mickey Buckins. This group backed up singers such as Aretha Franklin, Wilson Pickett, Clarence Carter, Bobbie Gentry, Etta James, and Candi Staton during recording sessions at FAME Studios.

Aretha Franklin recorded at FAME on only one occasion, in early 1967; her hit "I Never Loved a Man (The Way I Love You)" was recorded at that time, with the Swampers providing the accompaniment. The track "Do Right Woman, Do Right Man" was also recorded during that session. Franklin later publicly acknowledged Rick Hall "for the turning point in her career, taking her from a struggling artist" to a major music star. The entire LP might have been recorded at FAME, but after Franklin's husband Ted White started an altercation, producer Jerry Wexler decided to continue recording in New York, including "Respect", again using the Swampers for the accompaniment.