Genre painting (or petit genre) is the painting of genre art, which depicts aspects of everyday life by portraying ordinary people engaged in common activities. One common definition of a genre scene is that it shows figures to whom no identity can be attached either individually or collectively, thus distinguishing it from history paintings (also called grand genre) and portraits. A work would often be considered as a genre work even if it could be shown that the artist had used a known person—a member of his family, say—as a model. In this case it would depend on whether the work was likely to have been intended by the artist to be perceived as a portrait—sometimes a subjective question. The depictions can be realistic, imagined, or romanticized by the artist. Because of their familiar and frequently sentimental subject matter, genre paintings have often proven popular with the bourgeoisie, or middle class.

Genre subjects appear in many traditions of art. Painted decorations in ancient Egyptian tombs often depict banquets, recreation, and agrarian scenes, and Peiraikos is mentioned by Pliny the Elder as a Hellenistic panel painter of "low" subjects, such as survive in mosaic versions and provincial wall-paintings at Pompeii: "barbers' shops, cobblers' stalls, asses, eatables and similar subjects". Medieval illuminated manuscripts often illustrated scenes of everyday peasant life, especially in the Labours of the Months in the calendar section of books of hours, most famously the Très Riches Heures du Duc de Berry.

The Low Countries dominated the field until the 18th century. In the 17th century both Flemish Baroque painting and Dutch Golden Age painting produced numerous specialists who mostly painted genre scenes.

In the previous century, the Flemish Renaissance painter Jan Sanders van Hemessen painted innovative large-scale genre scenes, sometimes including a moral theme or a religious scene in the background in the first half of the 16th century. These were part of a pattern of "Mannerist inversion" in Antwerp painting, giving "low" elements previously in the decorative background of images prominent emphasis. In the second half of the 16th century, Pieter Aertsen and Joachim Beuckelaer painted in Antwerp works showing in the foreground cooks or market-sellers amidst a bountiful spread of vegetables, fruit and/or meat, with small religious scenes in spaces in the background. Around the same time, Pieter Brueghel the Elder made peasants and their activities, very naturalistically treated, the subject of many of his paintings.

Adriaen and Isaac van Ostade, Jan Steen, Adriaen Brouwer, David Teniers, Joos van Craesbeeck, Gillis van Tilborgh, Aelbert Cuyp, Willem van Herp, David Ryckaert III. Jacob Jordaens, Johannes Vermeer and Pieter de Hooch were among the many painters specializing in genre subjects in the Low Countries during the 17th century. The generally small scale of these artists' paintings was appropriate for their display in the homes of middle class purchasers.

The apparent 'realism' of 17th-century Dutch and Flemish art gives the viewer the initial impression that the artist solely intends to depict scenes of common life in a realistic way. Underneath the realistic representation are, however, often hidden underlying meanings, either moral or symbolic. For instance, Gabriel Metsu's The Poultry seller, 1662 shows an old poultry seller handing a young woman a live rooster with its head craning upwards. The suggestive pose of the rooster's head and the fact that the Dutch word for 'birds' (vogelen) was also a vulgar term for sexual intercourse indicated that the artist also included a scabrous meaning in his painting. Genre painters often included symbolic meanings in their paintings. For instance, Adriaen Brouwer painted a number of genre portraits that represent the five senses or the seven deadly sins. An example is his genre group portrait The Smokers which depicts the sense of taste. Other artists included moral meanings into their genre scenes. Jan Steen's The Happy Family painted in 1668 depicts a merry family evening with the head of the family, clearly inebriated, singing out his lungs, backed up by the mother and grandmother. The children join in on musical instruments. The moral of the picture is clarified in the note hanging from the mantelpiece reading "So de ouden songen, so pijpen de jongen" ("As the Old Sing, So the Young Pipe"), i.e. children will learn their behaviour from their parents. Jacob Jordaens had painted a series of paintings on the same subject matter about 30 years earlier.

One of the recurring themes in Flemish and Dutch genre painting is that of the merry company. These works typically show a group of figures at a party, whether making music at home or just drinking in a tavern. Other common types of scenes showed markets or fairs, village festivities ("kermesse"), or soldiers in their camp or guardroom.

The Dutch painter Pieter van Laer arrived in 1625 in Rome where he started to paint genre paintings incorporating scenes of the Roman Campagna. He also joined a loose organisation of Flemish and Dutch painters in Rome known as the Bentvueghels (Dutch for 'birds of a feather'). Van Laer was given the nickname "Il Bamboccio", which means "ugly doll" or "puppet". A number of Flemish and Dutch and later also Italian painters, who painted genre scenes of the Roman countryside inspired by van Laer's works were subsequently referred to as the Bamboccianti. The initial Bamboccianti included Andries and Jan Both, Karel Dujardin, Jan Miel and Johannes Lingelbach. Sébastien Bourdon was also associated with this group during his early career. Other Bamboccianti include Michiel Sweerts, Thomas Wijck, Dirck Helmbreker, Jan Asselyn, Anton Goubau, Willem Reuter, and Jacob van Staverden. Their whose works would inspire local artists Michelangelo Cerquozzi, Giacomo Ceruti, Antonio Cifrondi, and Giuseppe Maria Crespi among many others.