Tibetan Muslims, also known as the Khache (Tibetan: ཁ་ཆེ་, lit. 'Kashmiris'), are Tibetans who adhere to Islam. Many are descendants of Kashmiris, Ladakhis, and Nepalis who arrived in Tibet in the 14th to 17th centuries. There are approximately 10,000 Tibetan Muslims living in China, over 1,500 in India, and 300 to 400 in Nepal.

The government of the People's Republic of China does not recognize the Tibetan Muslims as a distinct ethnic group; they are grouped with Tibetan adherents of Buddhism and Bön. In contrast, the Chinese-speaking Hui Muslims are distinguished from the Han Chinese majority.

In Tibet, Tibetan Muslims are known as Khache, which literally translates as 'Kashmiri' in Tibetan, because many are descendants of pre-modern emigrants from Kashmir. In Nepal, they are split into two groups: the Khache, who have Kashmiri ancestry and therefore hold Indian passports; and the Khazar, who have Nepali ancestry and therefore hold Nepali passports.

The first contacts between Tibet and the Islamic world began around the mid-eighth century when it grew out of a combination of trade via the Silk Road and the military presence of Muslim forces in the Fergana Valley. Despite the vague knowledge the Islamic world had about Tibet, there were a few early Islamic works that mention Tibet. One such source is from a work authored by Abu Sa'id Gardezi titled Zayn al-Akhbar. In it, the work mentions the environment, fantastical origin of the Tibetans (through the Himyarites), the divinity of the king, major resources (like musk) and a description of the trade routes to and from Tibet. Another source, Hudud al-'Alam (The Regions of the World) written by an unknown author in 982 or 983 in Afghanistan, contains mainly geography, politics and brief descriptions of Tibetan regions, cities, towns and other localities. This source has the first direct mention of the presence of Muslims in Tibet by stating that Lhasa had one mosque and a small Muslim population.

During the reign of Sadnalegs (800–815), there was a protracted war against Arab powers to the West. It appears that Tibetans captured a number of Arab troops and pressed them into service on the eastern frontier in 801. Tibetans were active as far west as Samarkand and Kabul. Arab forces began to gain the upper hand, and the Tibetan governor of Kabul submitted to the Arabs and became a Muslim about 812 or 815.

Extensive trade with Kashmir, Ladakh, and Baltistan also brought Muslims to Tibet especially after the adoption or growing presence of Islam in these regions starting from the fourteenth century. The ongoing growth of Muslims continued as an effect of the Tibetan-Ladakhi treaty of 1684 in which the Tibetan government allowed trade missions from Ladakh to enter Lhasa every three years. Many Kashmiri and Ladakhi Muslims joined these missions with some settling in Tibet.

During the reign of the Dalai Lama Ngawang Lobsang Gyatso (1617–1682), a permanent Muslim community settled down in Tibet. They were permitted to elect their own council of representatives, settle their group's legal disputes with Islamic law, and some land was donated to them for the construction of a mosque close to Lhasa. The community soon adopted aspects of Tibetan culture like dress, diet, and the Tibetan language.

An influx of Kashmiri Muslims in Nepal (originally having trade contacts with their kin in Tibet) fled to Tibet starting from 1769 due to the invasion of the Kathmandu Valley by Prithvi Narayan Shah. As early as the seventeenth century, Ningxia and other northwestern Hui (Chinese Muslims) began to settle in the eastern regions of Tibet (like in Amdo). They intermarried with the local Tibetans and continued to have extensive trade contacts with other Muslims inside China.