Properidine

Properidine
Clinical data
Other names	Ipropethidine
ATC code	none;
Legal status
Legal status	AU: S9 (Prohibited substance); BR: Class A1 (Narcotic drugs); CA: Schedule I; DE: Anlage I (Authorized scientific use only); UK: Class A; US: Schedule I; UN: Psychotropic Schedule I;
Identifiers
	IUPAC name isopropyl 1-methyl-4-phenylpiperidine-4-carboxylate;
CAS Number	561-76-2 ;
PubChem CID	62373;
ChemSpider	56161 ;
UNII	R1493W1CJ0;
KEGG	D13025;
CompTox Dashboard (EPA)	DTXSID20204644 ;
ECHA InfoCard	100.008.385
Chemical and physical data
Formula	C16H23NO2
Molar mass	261.365 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OC(C)C)C2(c1ccccc1)CCN(C)CC2;
	InChI InChI=1S/C16H23NO2/c1-13(2)19-15(18)16(9-11-17(3)12-10-16)14-7-5-4-6-8-14/h4-8,13H,9-12H2,1-3H3 ; Key:XJKQCILVUHXVIQ-UHFFFAOYSA-N ;
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Properidine is an opioid, an analgesic, and the isopropyl analog of pethidine.^[2] Properidine is under international control and is listed in the United States under the Controlled Substances Act (1970) as a Schedule I substance. It is a narcotic, with an Administrative Controlled Substances Code Number (ACSCN) of 9644 and a 2 gramme annual aggregate manufacturing quota as of 2014. The salt in use is hydrochloride, with a free base conversion ratio of 0.88.^[3]

References

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ Morrison AL, Rinderknecht H (1950). "302. Synthetic analgesics. Part V. Compounds related to pethidine". Journal of the Chemical Society (Resumed): 1467. doi:10.1039/JR9500001467.
^ "Quotas - 2014". Diversion Control Division. U.S. Department of Justice, Drug Enforcement Administration.

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