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Celltrion
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Celltrion
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Celltrion Inc. is a South Korean biopharmaceutical company specializing in the research, development, manufacture, and commercialization of biosimilars and innovative biologic medicines, with a focus on monoclonal antibodies for treating conditions such as autoimmune diseases, oncology, and infectious diseases.[1] Founded in February 2002 and headquartered in Incheon, South Korea, Celltrion has grown into one of the world's largest biosimilar manufacturers, with annual revenues reaching 3.56 trillion KRW in 2024 and operating production facilities with a total capacity of 250,000 liters.[2][3][4]
The company pioneered the global biosimilars market by launching Remsima (infliximab), the world's first monoclonal antibody biosimilar, which received approval from the European Medicines Agency (EMA) in 2013, the U.S. Food and Drug Administration (FDA) in 2016, and the Korean Ministry of Food and Drug Safety (MFDS) in 2012, marking a significant advancement in affordable biologic therapies.[2] Celltrion's portfolio has since expanded to include other key biosimilars such as Truxima (rituximab, approved by EMA in 2017 and FDA in 2018), Herzuma (trastuzumab, approved by EMA in 2018 and FDA in 2018), Yuflyma (adalimumab, approved by EMA in 2021 and FDA in 2023), and Vegzelma (bevacizumab, approved by EMA and FDA in 2022), with products now approved in approximately 100 countries and biosimilar sales accounting for about 87% of its revenue.[2][3]
Celltrion invests approximately 20% of its revenue in research and development, with about 30% of its workforce dedicated to R&D, around 33% of employees holding advanced degrees, and maintains cGMP-certified facilities approved by the FDA and EMA since 2007 and 2015, respectively, enabling high-efficiency production.[1] Its global footprint includes subsidiaries like Celltrion USA (established 2018) and operations across Europe, Asia, and the Americas, supporting one-stop solutions from clinical trials to commercialization; in 2025, it acquired a biopharmaceutical manufacturing facility in New Jersey from Eli Lilly and Co. for US$330 million.[5] In recent years, the company has diversified through mergers, such as the 2023 integration of Celltrion Healthcare, and strategic acquisitions, including Takeda's primary care assets in 2020, while continuing to develop novel therapies like Regkirona (regdanvimab) for COVID-19, approved by the EMA in 2021.[2][6]
