Detonator Orgun (Japanese: デトネイター・オーガン, Hepburn: Detoneitā Ōgan) is a 1991 Japanese original video animation series by AIC and Artmic, directed by Masami Ōbari with character designs by Kia Asamiya.

Tomoru Shindo is a college student from City 5. He sleeps with a device that helps him explore frequencies similar to those emitted by the brain during sleep. Thereby he can record his own and other peoples thoughts and dreams through its amplifying capabilities. He picks up bits and pieces of information from an unspecified source that is slowly building into a dream of different nuances. Each night, it evolves around a woman suppressed by hostile actors in various dimensions and for every scenario, the two of them always stumble upon each other and barely slip out of harm's way. Puzzled and stricken each morning by the magnitude of the dreams, Tomoru tries to sync his hardware with the beacon. What he doesn't know is that the emitter is the fallen champion fighter Orgun, who was intercepted and subsequently assassinated on the Moon on his way to Earth. Pushed out of options and mortally wounded after his confrontation, as a last resort, he sent the signals that Tomoru has been exploring.

Another thing Tomoru doesn't know is that he isn't alone. Earth Defense Force (EDF) employee Professor Michi Kanzaki receives signals from the Moon. With the help of the super computer ISAC, she tries to compile the information in the data. She is unable to decipher the entirety of the signal, but its enough for her to understand its contents: a blueprint of an alien body! What she sees frightens her, and although she is hesitant to continue the work, she reluctantly gives way to the military's wishes.

Tomoru is steadily accessing deeper nuances of the compelling dream that comes together as Orgun, an alien madman that reveals to Tomoru parts of his life experiences. Frightened by what the feelings and memories from the fallen warrior show him, Tomoru is dragged into a psychosis. He slowly loses grip of his own reality as he is overburdened by Orgun's pain and torment. The latter is urging Tomoru as an entity in his mind that has taken hold to dive deeper, which sends Tomoru on the run. Tomoru is sinking deeper in the recesses of Orgun's memories and his urgent message to his spokesperson on Earth. A trinity develops between Tomoru, Professor Kanzaki, and the memories of Orgun held by Tomoru. However, what every party is asking themselves is why a being from such a technologically superior race has set his sights on Earth. Professor Kanzaki believes she doesn't want to know the answer to that question. Although if her employer wants to get their way, the answer to all of their questions lies within a young man who seems to have stumbled into her life's work.

The EDF create robotic suits based on Orgun in order to defend Earth. Orgun and Tomoru meet two of the Evoluder: Leave, who dies protecting Orgun, and Lang, who battles Orgun in anger for his treason. It is revealed that the Evoluder are the descendants of a crewed space mission Earth sent to the Cygnus constellation 200 years earlier, whose crew evolved into mechanical lifeforms due to experiencing millions of years of time dilation during the journey. Some of the Evoluder are telepathically linked to certain humans, such as Tomoru with Orgun and Kumi with the Evoluder's leader, Mhiku.

Using their robotic suits, the EDF repels the Evoluder's invasion force. Kumi uses her telekinetic powers to move the Sun so Orgun can save the Earth. Zoa, the Evoluder's military commander, fires the antimatter cannon. Orgun uses his Grand Cross attack to kill Zoa and destroy the cannon. Orgun crashes onto a beach and dies while Tomoru survives. Mhiku resumes ruling the Evoluder, who peacefully leave Earth. Tomoru and Kanzaki walk off into the sunset while Orgun's remains are displayed in a museum.

The series was released on DVD in 2001 by Central Park Media in the United States, in 2002 by Happinet Pictures in Japan, and as VHS in 1997 and as DVD in 2003 by Manga Entertainment in the United Kingdom.

Polydor K.K., a member of the series' production committee, recommended Susumu Hirasawa, an artist from their roster, to compose music for the series. Hirasawa took the role because of a wish to work with producer Satoshi Koizumi, whose personality drew Hirasawa in after requesting him to dispel the image that anime soundtracks had. The composer was asked to write the anime's main theme first, and it was presented to Koizumi and director Masami Ōbari in late 1990, before animation had started.