Methoxpropamine

Methoxpropamine

Legal status
Legal status	CA: Schedule I DE: NpSG (Industrial and scientific use only) UK: Class B
Identifiers
IUPAC name 2-(3-Methoxyphenyl)-2-(propylamino)cyclohexanone
CAS Number	2504100-71-2 Y
PubChem CID	155817932
ChemSpider	128909942
UNII	LTF83AU3X8
CompTox Dashboard (EPA)	DTXSID501336500
Chemical and physical data
Formula	C16H23NO2
Molar mass	261.365 g·mol−1
3D model (JSmol)	Interactive image
SMILES COc1cccc(c1)C2(NCCC)CCCCC2=O
InChI InChI=1S/C16H23NO2/c1-3-11-17-16(10-5-4-9-15(16)18)13-7-6-8-14(12-13)19-2/h6-8,12,17H,3-5,9-11H2,1-2H3 Key:AAVOSBAXDRASAH-UHFFFAOYSA-N

Methoxpropamine (MXPr, 2-Oxo-3'-methoxy-PCPr) is a dissociative anesthetic drug of the arylcyclohexylamine class and NMDA receptor antagonist^[1] that is closely related to substances such as methoxetamine and PCPr.^[2] It has been sold online as a designer drug, first being identified in Denmark in October 2019,^[3] and is illegal in Finland.^[4]

1. ^ Irie T, Yamazaki D, Kikura-Hanajiri R (July 2021). "A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice". Forensic Toxicology. 39 (2): 474–80. doi:10.1007/s11419-021-00571-0. S2CID 232273277.
2. ^ Goncalves R, Castaing N, Richeval C, Ducint D, Titier K, Morvan E, et al. (April 2022). "Methoxpropamine (MXPr) in powder, urine and hair samples: Analytical characterization and metabolite identification of a new threat". Forensic Science International. 333 111215. doi:10.1016/j.forsciint.2022.111215. PMID 35151938. S2CID 246685658.
3. ^ "EU Early Warning System Situation Report. Situation report 1" (PDF). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). June 2020.
4. ^ "Valtioneuvoston asetus kuluttajamarkkinoilta kielletyistä psykoaktiivisista aineista" [Government decree on psychoactive substances banned from the consumer market]. Finlex Data Bank (in Finnish). Finnish Ministry of Justice.

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