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Nancy Rothwell

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Nancy Rothwell

Dame Nancy Jane Rothwell DBE DL FRS FMedSci FRSB FBPhS MAE (born 2 October 1955) is a British physiologist. She served as president and vice-chancellor of the University of Manchester from 2010 to 2024, having deputised in both roles until January 2010.

Rothwell served as non-executive director of pharmaceuticals company AstraZeneca from 2006 to 2015. She also served as co-chair of the Council for Science and Technology, and past president of the Royal Society of Biology.

She served as Deputy Lieutenant of Greater Manchester and served as chair of the Russell Group from 2020 to 2023, which represents 24 of the research intensive universities in the UK. In March 2021, students at the University of Manchester passed a vote of no confidence in Rothwell due to her response to the COVID-19 pandemic in the United Kingdom.

Rothwell was born in Tarleton, a village near Preston, Lancashire. She was educated at Penwortham Girls' Grammar School and then went to college where she took A-levels in mathematics, physics, chemistry and art, having dropped biology aged 14. She enrolled at the University of London and obtained a first-class degree in physiology (1976) and a Doctor of Philosophy degree (1979) from Queen Elizabeth College (now part of King's College, London). Rothwell was awarded a Doctor of Science (DSc) degree in 1987 by King's College London.

Rothwell's early research identified mechanisms of energy balance regulation, obesity and cachexia. In 1984 she was awarded a Royal Society University Research Fellowship[citation needed] and numerous grants by the Biotechnology and Biological Sciences Research Council (BBSRC). She was appointed to a chair in physiology in 1994, then a Medical Research Council (MRC) research chair in 1998. Her current research focusses on the role of inflammation in brain disease and has identified the role of the cytokine interleukin-1 (IL-1) in diverse forms of brain injury. Her studies have begun to elucidate the mechanisms regulating IL-1 release and its action and her group have conducted the first early clinical trial of an IL-1 inhibitor in strokes. She served as president of the British Neuroscience Association and a council member of Medical Research Council (MRC).[when?]

From October 2004, Rothwell served as vice-president for research of the university. In 2010 she was overseeing a research group of about 20 scientists, with significant external funding and was announced to succeed Alan Gilbert as president and vice-chancellor of the University of Manchester on 1 July 2010. She is a trustee of Cancer Research UK, the Campaign for Medical Progress, a council member of BBSRC, chair of the Research Defence Society and the Wellcome Trust's Public Engagement Strategy Committee and a non-executive director of AstraZeneca. In 1998 she delivered the Royal Institution Christmas Lecture on The Secrets of Life, televised by the BBC.

In January 2010, Rothwell was appointed deputy president and deputy vice-chancellor. Until Alan Gilbert retired she was acting president due to his sick leave. On 21 June 2010, she was appointed president and vice-chancellor of the University of Manchester. She assumed her post on 1 July 2010, succeeding Gilbert, who had retired after nearly six years. She became the first woman to lead the University of Manchester or either of its two predecessor institutions. Commenting on her appointment, she said: "I am honoured and delighted to be invited to lead the University at this exciting time. I am determined to maintain the strategic focus that we have developed over the past six years and to work closely with colleagues to identify new priorities and opportunities for the University in the very challenging external environment that we will face over the next few years."

The chairman of the appointment panel and chairman-elect of the university's board of governors, Anil Ruia, said: "Dame Nancy will bring her own distinctive strengths, perspective and style to the role of President and Vice-Chancellor which will enable the University to build upon the remarkable progress that we have made under Professor Alan Gilbert's leadership." In 2009, Rothwell served as the first president of the Society of Biology.[citation needed]

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