Null modem is a communication method to directly connect two DTEs (computer, terminal, printer, etc.) using an RS-232 serial cable. The name stems from the historical use of RS-232 cables to connect two teleprinter devices or two modems in order to communicate with one another; null modem communication refers to using a crossed-over RS-232 cable to connect the teleprinters directly to one another without the modems. It is also used to serially connect a computer to a printer, since both are DTE, and is known as a Printer Cable.

The RS-232 standard is asymmetric as to the definitions of the two ends of the communications link, assuming that one end is a DTE and the other is a DCE, e.g. a modem. With a null modem connection the transmit and receive lines are crosslinked. Depending on the purpose, sometimes also one or more handshake lines are crosslinked. Several wiring layouts are in use because the null modem connection is not covered by the RS-232 standard.

Originally, the RS-232 standard was developed and used for teleprinter machines which could communicate with each other over phone lines. Each teleprinter would be physically connected to its modem via an RS-232 connection and the modems could call each other to establish a remote connection between the teleprinters. If a user wished to connect two teleprinters directly without modems (null modem) then they would crosslink the connections. The term null modem may also refer to the cable or adapter itself as well as the connection method. Null modem cables were a popular method for transferring data between the early personal computers from the 1980s to the early 1990s.

A null modem cable is a RS-232 serial cable where the transmit and receive lines are crosslinked. In some cables there are also handshake lines crosslinked. In many situations a straight-through serial cable is used, together with a null modem adapter. The adapter contains the necessary crosslinks between the signals.

Below is a very common wiring diagram for a null modem cable to interconnect two DTEs (e.g. two PCs) providing full handshaking, which works with software relying on proper assertion of the Data Carrier Detect (DCD) signal:

The original application of a null modem was to connect two teleprinter terminals directly without using modems. As the RS-232 standard was adopted by other types of equipment, designers needed to decide whether their devices would have DTE-like or DCE-like interfaces. When an application required that two DTEs (or two DCEs) needed to communicate with each other, then a null modem was necessary.

Null modems were commonly used for file transfer between computers, or remote operation. Under the Microsoft Windows operating system, the direct cable connection can be used over a null modem connection. The later versions of MS-DOS were shipped with the InterLnk program. Both pieces of software allow the mapping of a hard disk on one computer as a network drive on the other computer. No Ethernet hardware (such as a network interface card or a modem) is required for this. On the Amiga computer, a null modem connection was a common way of playing multiplayer games between two machines.

The popularity and availability of faster information exchange systems such as Ethernet made the use of null modem cables less common. In modern systems, such a cable can still be useful for kernel mode development, since it allows the user to remotely debug a kernel with a minimum of device drivers and code (a serial driver mainly consists of two FIFO buffers and an interrupt service routine). KGDB for Linux, ddb for BSD, and WinDbg or KD for Windows can be used to remotely debug systems, for example. This can also provide a serial console through which the in-kernel debugger can be dropped to in case of kernel panics, in which case the local monitor and keyboard may not be usable anymore (the GUI reserves those resources and dropping to the debugger in the case of a panic won't free them).