Regina Lee Hall (born December 12, 1970) is an American actress. She gained prominence for her portrayal of Brenda Meeks in the comedy-horror Scary Movie film series and has since built a versatile career spanning comedy and drama in both film and television. In 2018, Hall became the first African-American to win the New York Film Critics Circle Award for Best Actress for her performance in the film Support the Girls.

Hall made her film debut in The Best Man (1999) and reprised her role in its sequel The Best Man Holiday (2014). Her notable film credits include Love & Basketball (2000), Think Like a Man (2012) and its sequel Think Like a Man Too (2014), Girls Trip (2017), The Hate U Give (2018), and One Battle After Another (2025). On television, she has starred in the comedy-drama series Ally McBeal (2001–2002), NBC police procedural Law & Order: LA (2010–2011), the comedy series Black Monday (2019–2021), and appeared as Ninny in Issa Rae's Insecure (2017).

In 2022, she co-hosted the 94th Academy Awards alongside Amy Schumer and Wanda Sykes.

Hall was born the daughter of a contractor and electrician father, Odie Hall, and a teacher mother, Ruby. After graduating from Immaculata High School, Hall enrolled at Fordham University in the Bronx, where she graduated with a bachelor's degree in English in 1992. She later enrolled at New York University, where she earned a master's degree in journalism in 1997. Reflecting on college, Hall said: "I loved being a student. I could've gone to school until I was 75 years old as long as somebody would've paid my rent. I would've been a professional student."

She wanted a career with impact and envisioned a career in writing or journalism, but Hall's first semester of graduate school changed drastically when her father died of a stroke. "It was sudden. And I think when sudden events that are painful happen in your life, you know, they redirect your course," Hall reflected. "When you're young, you don't grasp the gravity of life. But when you lose someone that you spend most of your life with, and you're young, you do. And so I think that started me thinking about what I really wanted to do in life. And I know my father would have wanted me to finish school. So I did that." She began a career in the entertainment industry, starting off with a guest appearance on Sadat X's 1996 album Wild Cowboys on the track, "The Interview".

In 1997, Hall appeared in her first television commercial at the age of 26. Her television career began with a role on the soap opera Loving, and guest appearances on the Fox police drama New York Undercover. She played Candy in the 1999 film The Best Man. She left a lasting impression on viewers with her portrayal of the character Candace "Candy" Sparks. Hall reflected: "It was my very first movie. I met Sanaa Lathan on it, and we did Love and Basketball together, which was my second film. And then, at that point, I was visiting L.A. to stay and it led to a third film and a fourth film. And it was really a big deal because I'd never been on a set before."

Hall gained more recognition with her role in the comedy-horror-spoof Scary Movie (and the sequels Scary Movie 2, Scary Movie 3, and Scary Movie 4) portraying the sex-crazed Brenda Meeks, and the TV movie Disappearing Acts. The Scary Movie films would become some of her best known roles. In 2001, Hall landed the role of Coretta Lipp on the prime-time drama Ally McBeal, which was originally a recurring role over several episodes but was made a main character in the 5th season of the show. A year later, she starred in the action-drama Paid in Full, a film directed by Charles Stone III. Since then, she has appeared in leading roles in films such as Malibu's Most Wanted, King's Ransom and The Honeymooners.

She appeared in the film Law Abiding Citizen in 2009. She had a role in the 2010 Danneel Harris and Arielle Kebbel film Mardi Gras. From its fall 2010 debut until a series overhaul in January 2011, Regina Hall portrayed Deputy District Attorney Evelyn Price on Law & Order: LA.