Sterol esterase

The enzyme sterol esterase (EC 3.1.1.13) catalyzes the reaction

a sterol ester + H₂O ${\displaystyle \rightleftharpoons }$ a sterol + a fatty acid

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is steryl-ester acylhydrolase. Other names in common use include cholesterol esterase, cholesteryl ester synthase, triterpenol esterase, cholesteryl esterase, cholesteryl ester hydrolase, sterol ester hydrolase, cholesterol ester hydrolase, cholesterase, and acylcholesterol lipase. This enzyme participates in bile acid biosynthesis.

• Hyun J, Kothari H, Herm E, Mortenson J, Treadwell CR, Vahouny GV (1969). "Purification and properties of pancreatic juice cholesterol esterase". J. Biol. Chem. 244 (7): 1937–45. doi:10.1016/S0021-9258(18)91769-2. PMID 5780846.
• Okawa Y, Yamaguchi T (May 1977). "Studies on sterol-ester hydrolase from Fusarium oxysporum. I Partial purification and properties". J. Biochem. 81 (5). Tokyo: 1209–15. PMID 19426.
• Vahouny GV, Treadwell CR (1968). "Enzymatic synthesis and hydrolysis of cholesterol esters". Methods of Biochemical Analysis. Vol. 16. pp. 219–72. doi:10.1002/9780470110348.ch4. ISBN 978-0-470-11034-8. PMID 4877146.
• Warnaar F (1987). "Triterpene ester synthesis in latex of Euphorbia species". Phytochemistry. 26 (10): 2715–2721. Bibcode:1987PChem..26.2715W. doi:10.1016/S0031-9422(00)83578-5.

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