Catherine Jeanne Béatrice Colonna (French: [katʁin kɔlɔna]; born 16 April 1956) is a French diplomat and politician who served as Minister for Europe and Foreign Affairs in the government of Prime Minister Élisabeth Borne from May 2022 to January 2024.

Colonna previously served as Ambassador of France to the United Kingdom (2019–2022), Ambassador of France to Italy (2014–2017), Permanent Representative to OECD (2017–2019) and Permanent Representative to UNESCO (2008–2010).

Colonna was born in Tours in the Centre-Val de Loire region. Colonna was the daughter of a farmer of Corsican origin. After obtaining a master's degree in public law at the Université François-Rabelais of Tours, she pursued her studies at the Institut d'études politiques de Paris (public service) then École nationale d'administration (ENA) in the class of 1983 (Promotion Solidarité).

In 1983, Colonna entered diplomatic service being appointed to the Embassy of France in the United States, first in the political department, then in the press and information department.

Upon her return to Paris, Colonna oversaw European Law at the Legal Affairs Directorate of the Ministry of Foreign Affairs from 1986 to 1988. In 1988, she was promoted Technical Advisor in Minister of Public Works Maurice Faure's cabinet, under the presidency of François Mitterrand. In 1989, shortly before the fall of the Berlin Wall, she joined the Analysis and Forecasting Centre at the Ministry of Foreign Affairs, where she was put in charge of European Affairs. She later became spokeswoman of the Ministry of Foreign Affairs in 1990, in the department of Communication and Information, a position she held for five years.

In 1993, Minister of Foreign Affairs Alain Juppé and Cabinet Director Dominique de Villepin named Colonna deputy spokeswoman. Two years later, in May 1995, newly-installed President Jacques Chirac appointed her spokeswoman for the Élysée. For the following nine years, she served as the official voice of the French Republic's presidency, then left office to work as Director General of the National Centre of Cinematography (CNC) in September 2004.

Following the European Constitution referendum, Colonna returned to diplomacy, being appointed Minister Delegate for European Affairs in Prime Minister Dominique de Villepin's newly-formed government on 2 June 2005. She remained in position for two years, until 15 May 2007. From autumn 2007 until summer 2008, Colonna participated in the Commission on the White Paper on Foreign and European policy of France, led by Alain Juppé.

On 26 March 2008, Colonna was appointed the French Permanent Representative to UNESCO.