Parthenocissus /ˌpɑːrθɪnoʊˈsɪsəs/, is a genus of tendril climbing plants in the grape family, Vitaceae. It contains about 12 species native to the Himalaya, eastern Asia and North America. Several are grown for ornamental use, notably P. henryana, P. quinquefolia and P. tricuspidata.

The name derives from the Greek παρθένος (parthenos) "virgin", and κισσός (kissós) (Latinized as "cissus"), "ivy".[1] The reason is variously given as the ability of these creepers to form seeds without pollination or the English name of P. quinquefolia, Virginia creeper, which has become attached to the whole genus.

Among the middle Miocene Sarmatian palynoflora from the Lavanttal Basin, Austrian researchers have recognized Parthenocissus fossil pollen. The sediment containing the Parthenocissus fossil pollen had accumulated in a lowland wetland environment with various vegetation units of mixed evergreen/deciduous broadleaved/conifer forests surrounding the wetland basin. Key relatives of the fossil taxa found with Parthenocissus are presently confined to humid warm temperate environments, suggesting a subtropical climate during the middle Miocene in Austria.

Parthenocissus species are used as food plants by the larvae of some Lepidoptera species including the brown-tail, Gothic, and the Virginia creeper sphinx.