Sehwan (Sindhi: سيوهڻ شريف; Urdu: سہون شریف), also commonly referred to as Sehwan Sharif (meaning Noble Sehwan) is a historic city located in Jamshoro District of the Sindh province in Pakistan. It is situated on the west bank of the Indus River, approximately 130 kilometers (80 miles) northwest of Hyderabad, Sindh. The city is best known for being the site of one of Pakistan's most prominent Sufi shrines, the Shrine of Lal Shahbaz Qalandar. Sehwan holds the administrative status of a taluka within the Jamshoro District. Historically, it was part of the Dadu District until the creation of Jamshoro District, when it was incorporated into the new administrative unit.

Sehwan is recognized as one of Pakistan's most significant spiritual and pilgrimage centers. It holds a central place in the country's Sufi heritage, alongside other prominent shrines such as the Shrine of Abdullah Shah Ghazi in Karachi, the Data Durbar Complex in Lahore, Bari Imam in Noorpur Shahan near Islamabad, and the revered tombs of the Suhrawardi Sufis in Multan. These sites collectively reflect the deep-rooted Sufi traditions that have shaped the religious and cultural landscape of the region for centuries.

Sehwan is considered one of the most ancient cities of Sindh, Pakistan. According to various historical traditions, the origins of Sehwan trace back to antiquity . It was originally known as " Sivisthan " named after ancient Sivi janapada, which eventually evolved into Sehwan after Turk invasion of Sindh.

Syed Muhibullah, in A Brief History of Sindh, records another tradition claiming that Sehwan was named after a great-grandson of Ham (son of Noah). Meanwhile, British author William Dalrymple suggests that the name derives from Shivistan, referencing the Hindu deity Shiva.

Historian Molai Sheedai, in his book Tarikh-e-Tamaddun-e-Sindh, attributes the city's foundation to the Sewi Aryans, thus calling it Sewistan. Another scholarly view identifies the city as ancient Sindomana, a name frequently mentioned in Greek historical sources. The Sanskrit term Sindhu-mán means "the possessor or ruler of Sindh," and its variant Sindhu-ván may have evolved phonetically into Sehwan over time.

Sindomana is believed to have been the capital of King Sambos, who was defeated by Alexander during his campaign in the region in 326 BC. A prominent archaeological mound known as Kafir Qila ("Fort of the Pagans") lies to the north of the city and is associated with this period.

Sehwan was conquered by Muhammad bin Qasim in 711 CE during his expedition into Sindh, seizing it from the son of Raja Dahir. Later, in 1026 CE, the city was again captured by Mahmud of Ghazni.

Throughout the medieval period, Sehwan played a significant role in the political dynamics of the region. It was successively ruled by the Sumra, Samma, Arghun, and Tarkhan dynasties. During the rule of the Thatta Kingdom, Sehwan served as its capital. An unsuccessful attempt to capture Sehwan was made by the Mughal emperor Humayun in 1542 during his march to Umarkot, but the city eventually fell to his son Akbar in 1590s.