Darksiders II is an action role-playing hack and slash video game developed by Vigil Games and published by THQ. It is the sequel to Darksiders and was released in August 2012 for Microsoft Windows, PlayStation 3, Xbox 360 and as a launch title for Wii U upon the console's North American and PAL regions release in November of the same year. The story follows the efforts of player character Death to clear the name of his brother, War, who stands accused of wiping out humanity. On a total budget of $50 million, it was one of the most expensive video games to develop of all time.

A ported version, titled Darksiders II: Deathinitive Edition, was published by Nordic Games for the PlayStation 4, Xbox One and Microsoft Windows in 2015, ported to the Nintendo Switch in 2019, and released in Google Stadia in 2021. A parallel sequel, Darksiders III, was released in November 2018, while a spin-off prequel, Darksiders Genesis, was released in December 2019.

Players take control of Death, one of the Four Horsemen of the Apocalypse. The core gameplay is an action role-playing hack and slash style. The game makes frequent use of interactive puzzle elements, requiring the player to think their way through a series of levers, doors, elevators, portals, etc. in order to traverse areas and reach objectives. Which most of the time requires a key or a specific power to pass through.

Maps are vast and each contain open world regions that can be explored freely on foot or by his horse Despair, along with numerous dungeons where quest objectives are generally carried out. There are main and side quests, with main and side boss fights. Worlds can be traversed via fast travel, whereby the player can teleport to certain map points instantly. While inside a dungeon, the player is allowed to fast travel back to the overworld while saving their dungeon location for continuation later without losing progress.

Death is aided by Despair, a horse that is available for use in open areas of the overworld for faster travel, and Dust, a raven that guides him to his objectives. Death's primary weapons are two scythes, one wielded in each hand. Secondary weapons include melee weapons like hammers, axes, and maces as "slow" options; "fast" options are generally gauntlet-style weapons that provide the player with claws and other bladed arm extensions, at the expense of less range and power than the slow weapons.

There are several different movement options, including swimming, running along walls, and climbing options that are available on specially placed wooden elements, such as wall pegs and beams. In the course of quests, Death acquires "Death Grip", which operates as a grappling hook on certain objects; and "Voidwalker". Other abilities like "Soul Splitter" and "Interdiction" are acquired, which allow the player to control multiple characters to traverse puzzle areas.

Health, Wrath, and Reaper resource meters display on-screen whenever they change, along with an experience meter that shows how close the player is to the next character class level. Wrath is the game's mana-type system, being a resource used for special abilities. Reaper is a separate resource used for the Reaper ability, and when full, Death can transform briefly into his grim reaper form, which is more resilient and deals more damage.

There are eight player statistics, including a character class level that increases at various experience levels. Each new level gives the player a skill point that can be used in a skill tree that contains new abilities. Other statistics can be increased by equipping items, with each item having various stat-altering characteristics. The player's inventory contains seven different pages of equipment classes (primary and secondary weapon, shoulder, armor, glove, boot, and talisman, with an additional page for quest items). New equipment can be acquired via enemy drops, looting chests, or purchasing from vendor characters. New combo moves can also be purchased from "Trainer" characters.