Lily-Rose Melody Depp (born 27 May 1999) is a French and American actress. Born to actors Johnny Depp and Vanessa Paradis, she began her acting career in film with a minor role in Tusk (2014) and pursued a career as a fashion model. She appeared in the period dramas The Dancer (2016) and The King (2019), and the romantic comedy A Faithful Man (2018).

In 2023, Depp starred in the HBO television drama series The Idol and contributed to its soundtrack with her single "One of the Girls", which charted on the Billboard Hot 100 and surpassed one billion streams on Spotify. She received praise for her starring role in the horror film Nosferatu (2024).

Lily-Rose Melody Depp was born in the American Hospital of Paris located in Neuilly-sur-Seine, a wealthy suburb of Paris on 27 May 1999. She is the daughter of American actor Johnny Depp and French singer and actress Vanessa Paradis. She has a younger brother, Jack (John Christopher Depp III). French actress Alysson Paradis is her aunt.

On her father's side, she is of primarily English descent, with some French, German and Irish descent, as well as African descent through an eighth great-grandmother of her father, Elizabeth Key Grinstead, the first African American in the North American colonies to sue for her freedom and win in 1656.

Depp is the goddaughter of novelist François-Marie Banier and singer Marilyn Manson. Since her birth, she has been the subject of tabloid and media reporting, including birthdays, attendance at society events, and reviews of her fashion choices.

In 2012, after 14 years together, Depp's parents separated and arranged joint custody of her. She divides her time between Los Angeles, Paris, and New York City. Depp dropped out of high school in 2016 to focus on her acting career.

Depp made her acting debut in 2014, with a minor role in the horror comedy film Tusk. In 2015, at age 16, Depp began her modeling career as a brand ambassador for the French fashion house Chanel, in a decision personally overseen by Karl Lagerfeld (In 1991, her mother was also an ambassador, and promoted the fragrance Coco for Chanel, in an advertisement shot by Jean-Paul Goude.) Depp has since become closely associated with Chanel, serving as one of its most prominent faces. She has also modeled for the brand on runways and in numerous fashion magazines, including Vogue, Glamour, Elle, i-D, Wonderland, Love, Madame Figaro, W, and V.

In 2016, Depp reprised her Tusk role in the spin-off Yoga Hosers. She then landed her first major role portraying the American dancer Isadora Duncan in The Dancer, which premiered at the Cannes Film Festival in the Un Certain Regard category. For her performance in the film, Depp was nominated for Most Promising Actress at the 42nd César Awards and Best Female Revelation at the 22nd Lumières Awards. She also appeared in the film Planetarium alongside Natalie Portman, who handpicked Depp to play her younger sister. In that same year, Depp was made the face of Chanel's iconic fragrance Chanel No. 5 L'Eau.