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GPR78
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| GPR78 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | GPR78, G protein-coupled receptor 78 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 606921; HomoloGene: 50960; GeneCards: GPR78; OMA:GPR78 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.[3][4]
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][4]
References
[edit]- ^ a b c GRCh38: Ensembl release 89: ENSG00000155269 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
- ^ a b "Entrez Gene: GPR78 G protein-coupled receptor 78".
Further reading
[edit]- van Laar T, Schouten T, Hoogervorst E, Van Eck M, Van Der Eb AJ, Terleth C (2000). "The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9. PMID 10708769. S2CID 6419566.
- Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Underwood SL, Christoforou A, Thomson PA, Wray NR, Tenesa A, Whittaker J, Adams RA, Le Hellard S, Morris SW (2006). "Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia". Mol. Psychiatry. 11 (4): 384–94. doi:10.1038/sj.mp.4001786. PMID 16389273. S2CID 12678399.
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