Mount Druitt is a suburb of Sydney, in the state of New South Wales, Australia. It is located 43 kilometres (27 mi) west of the Sydney central business district, in the local government area of the City of Blacktown, and is part of the Greater Western Sydney region.

There are numerous encompassing, smaller suburbs nearby including Bidwill, Blackett, Dharruk, Emerton, Hebersham, Lethbridge Park, Minchinbury, Shalvey, Tregear, Whalan, and Willmot.

Major George Druitt (1773–1842) was granted 2,000 acres (8.1 km²) in the area by Governor Macquarie. He named his grant, where he died in 1842, Mount Druitt.

In April 2006, the Attorney General's Department of New South Wales opened a new court house at a cost of A$12 million. This was to become the first metropolitan area courthouse to utilise "circle sentencing", with aims to reduce over representation of Aboriginal Australians in custody.

A local landmark is the Georgian cottage known as The Manse, situated in The Avenue. It was probably built by John Harris in the mid-1880s; the land on which it was built was originally part of Druitt's property. Later it was sold to Robert Kennedy. Kennedy left it to the Presbyterian Church when he died, and it was used for some time as a manse. It was acquired by Blacktown City Council in 2000 and restored. It is now the headquarters of the Mt Druitt Historical Society and is open to the public. It has both a local government and state government heritage listing.

Mount Druitt has a number of heritage-listed sites, including:

The first electric train to Mount Druitt operated 8 October 1955.

Mount Druitt High school was established in the 1960s.