Mathematics and art are related in a variety of ways. Mathematics has itself been described as an art motivated by beauty. Mathematics can be discerned in arts such as music, dance, painting, architecture, sculpture, and textiles. This article focuses, however, on mathematics in the visual arts.

Mathematics and art have a long historical relationship. Artists have used mathematics since the 4th century BC when the Greek sculptor Polykleitos wrote his Canon, prescribing proportions conjectured to have been based on the ratio 1:√2 for the ideal male nude. Persistent popular claims have been made for the use of the golden ratio in ancient art and architecture, without reliable evidence. In the Italian Renaissance, Luca Pacioli wrote the influential treatise De divina proportione (1509), illustrated with woodcuts by Leonardo da Vinci, on the use of the golden ratio in art. Another Italian painter, Piero della Francesca, developed Euclid's ideas on perspective in treatises such as De Prospectiva Pingendi, and in his paintings. The engraver Albrecht Dürer made many references to mathematics in his work Melencolia I. In modern times, the graphic artist M. C. Escher made intensive use of tessellation and hyperbolic geometry, with the help of the mathematician H. S. M. Coxeter, while the De Stijl movement led by Theo van Doesburg and Piet Mondrian explicitly embraced geometrical forms. Mathematics has inspired textile arts such as quilting, knitting, cross-stitch, crochet, embroidery, weaving, Turkish and other carpet-making, as well as kilim. In Islamic art, symmetries are evident in forms as varied as Persian girih and Moroccan zellige tilework, Mughal jali pierced stone screens, and widespread muqarnas vaulting.

Mathematics has directly influenced art with conceptual tools such as linear perspective, the analysis of symmetry, and mathematical objects such as polyhedra and the Möbius strip. Magnus Wenninger creates colourful stellated polyhedra, originally as models for teaching. Mathematical concepts such as recursion and logical paradox can be seen in paintings by René Magritte and in engravings by M. C. Escher. Computer art often makes use of fractals including the Mandelbrot set, and sometimes explores other mathematical objects such as cellular automata. Controversially, the artist David Hockney has argued that artists from the Renaissance onwards made use of the camera lucida to draw precise representations of scenes; the architect Philip Steadman similarly argued that Vermeer used the camera obscura in his distinctively observed paintings.

Other relationships include the algorithmic analysis of artworks by X-ray fluorescence spectroscopy, the finding that traditional batiks from different regions of Java have distinct fractal dimensions, and stimuli to mathematics research, especially Filippo Brunelleschi's theory of perspective, which eventually led to Girard Desargues's projective geometry. A persistent view, based ultimately on the Pythagorean notion of harmony in music, holds that everything was arranged by Number, that God is the geometer of the world, and that therefore the world's geometry is sacred.

Polykleitos the elder (c. 450–420 BC) was a Greek sculptor from the school of Argos, and a contemporary of Phidias. His works and statues consisted mainly of bronze and were of athletes. According to the philosopher and mathematician Xenocrates, Polykleitos is ranked as one of the most important sculptors of classical antiquity for his work on the Doryphorus and the statue of Hera in the Heraion of Argos. While his sculptures may not be as famous as those of Phidias, they are much admired. In his Canon, a treatise he wrote designed to document the "perfect" body proportions of the male nude, Polykleitos gives us a mathematical approach towards sculpturing the human body.

The Canon itself has been lost but it is conjectured that Polykleitos used a sequence of proportions where each length is that of the diagonal of a square drawn on its predecessor, 1:√2 (about 1:1.4142).

The influence of the Canon of Polykleitos is immense in Classical Greek, Roman, and Renaissance sculpture, with many sculptors following Polykleitos's prescription. While none of Polykleitos's original works survive, Roman copies demonstrate his ideal of physical perfection and mathematical precision. Some scholars argue that Pythagorean thought influenced the Canon of Polykleitos. The Canon applies the basic mathematical concepts of Greek geometry, such as the ratio, proportion, and symmetria (Greek for "harmonious proportions") and turns it into a system capable of describing the human form through a series of continuous geometric progressions.

In classical times, rather than making distant figures smaller with linear perspective, painters sized objects and figures according to their thematic importance. In the Middle Ages, some artists used reverse perspective for special emphasis. The Muslim mathematician Alhazen (Ibn al-Haytham) described a theory of optics in his Book of Optics in 1021, but never applied it to art. The Renaissance saw a rebirth of Classical Greek and Roman culture and ideas, among them the study of mathematics to understand nature and the arts. Two major motives drove artists in the late Middle Ages and the Renaissance towards mathematics. First, painters needed to figure out how to depict three-dimensional scenes on a two-dimensional canvas. Second, philosophers and artists alike were convinced that mathematics was the true essence of the physical world and that the entire universe, including the arts, could be explained in geometric terms.