An anadrome is a word or phrase whose letters can be reversed to spell a different word or phrase. For example, desserts is an anadrome of stressed. An anadrome is therefore a special type of anagram. The English language is replete with such words.

The word anadrome comes from Greek anádromos (ἀνάδρομος), "running backward", and can be compared to palíndromos (παλίνδρομος), "running back again" (whence palindrome).

There is a long history (dating at least to the fourteenth century, as with Trebor and S. Uciredor) of alternate and invented names being created out of anadromes of real names; a proper noun conceived in this way is sometimes called an ananym, especially if it is used as personal pseudonym. Unlike typical anadromes, these anadromic formations often do not conform to any real names or words. Similarly cacographic anadromes are also characteristic of Victorian back slang, where for example yob stands for boy.

The English language has a very large number of single-word anadromes, by some counts more than 900. Examples include:

An anadrome can also be a phrase, as in no tops ↔ spot on. The word redrum (i.e., "red rum") is used this way for murder in the Stephen King novel The Shining (1977) and its film adaptation (1980).

Anadromes exist in other written languages as well, as can be seen, for example, in Spanish orar ↔ raro or French l'ami naturel ("the natural friend") ↔ le rut animal ("the animal rut").

Many jazz titles were written by reversing names or nouns: Ecaroh inverts the spelling of its composer Horace Silver's Christian name. Sonny Rollins dedicated to Nigeria a tune called "Airegin".

A number of Pokémon species, such as the snake Pokémon Ekans and Arbok (cobra backwards with a K), have anadromic names.