MS Queen Elizabeth (QE) is a cruise ship of the Vista class operated by the Cunard Line. The design is modified compared to earlier ships of the same class, and slightly larger than Queen Victoria, at 92,000 GT.

The ship's name was announced by Cunard on 10 October 2007. Since the retirement of Queen Elizabeth 2 in 2008 the company has operated four vessels. The naming of the ship as Queen Elizabeth brings about a situation similar to that between 1940 and 1948, when Cunard's original Queen Elizabeth was in service at the same time as the Royal Navy battleship HMS Queen Elizabeth.

Queen Elizabeth is similar in design to Queen Victoria; however, the steeper stern allowed a slightly higher passenger capacity of up to 2,058 compared to Queen Victoria's 2,014.

Also unlike many previous Cunard Queens, Queen Elizabeth is not a true ocean liner as she does not have the heavy plating throughout the hull. However, the bow was constructed with heavier plating to cope with the transatlantic run, and the ship has a high freeboard.

Although having an almost identical interior arrangement to Queen Victoria, the decor is very different. The ship is a tribute to the two previous Queen Elizabeth-named ships: the original Queen Elizabeth and Queen Elizabeth 2. She also evokes the era of the 1930s, in which Cunard's first Queen Elizabeth was launched, with many art deco interior touches. The ship also features a Britannia Club section of the main restaurant, which is a feature on Queen Mary 2, but not available on Queen Victoria. This service allows passengers in the Britannia staterooms to have single seating dining arrangements, without having to upgrade to the more expensive Grills classes. The sliding roof over the Winter Garden featured on Queen Victoria is replaced with a simple glass roof with the space being renamed the Garden Lounge.

Following the ship's construction in Italy from 2007 to 2010, Cunard Line officially confirmed that Queen Elizabeth II would name Cunard's new ship. The ceremony was held in Southampton on 11 October 2010 before the ship set sail on her maiden voyage to the Canary Islands the following day. Queen Elizabeth II was also the sponsor of the now-retired Queen Elizabeth 2 in 1967 and Cunard's current flagship, Queen Mary 2, in 2004.

The first master of Queen Elizabeth was Captain Christopher Wells. On 4 October 2010 Queen Elizabeth was formally handed over to Cunard. She sailed on her maiden voyage from Southampton on 12 October 2010, following a naming ceremony with the monarch on 11 October 2010.

On 13 January 2011, two years after the first Cunard Royal Rendezvous, RMS Queen Mary 2 met up with Queen Victoria and the then brand new Queen Elizabeth for another Royal Rendezvous in New York City. Both Queen Victoria and Queen Elizabeth made an Atlantic crossing in tandem for the event. All three Cunarders met in front of the Statue of Liberty at 6:45 pm for a Grucci fireworks display. The Empire State Building was lit up in red to mark the event. At the end of October 2011 Queen Elizabeth and her fleet mates were registered to Hamilton, Bermuda, in order to host weddings aboard.