Cape Coloureds (Afrikaans: Kaapse Kleurlinge) are a South African group of Coloureds who are from the Cape region in South Africa which consists of the Western Cape, Northern Cape and the Eastern Cape. Their ancestry comes from the interracial mixing between the European, the indigenous Khoi and San, the Xhosa plus other Bantu people, indentured labourers imported from the British Raj, slaves imported from the Dutch East Indies, immigrants from the Levant or Yemen (or a combination of all). Eventually, all these ethnic and racial groups intermixed with each other, forming a group of mixed-race people that became known as the "Cape Coloureds".

Although Coloureds represent only 8.15% of people within South Africa, they make up 42.1% of the population in the Western Cape, representing a plurality of the population of the province. (according to the 2022 South African census)

They are generally bilingual, speaking Afrikaans and English, though some speak only one of these. Some Cape Coloureds may code switch, speaking a patois of Afrikaans and English called Afrikaaps, also known as Cape Slang (Capy) or Kombuis Afrikaans, meaning Kitchen Afrikaans. Cape Coloureds were classified under apartheid as a subset of the larger Coloured race group.

Recent studies of Cape Coloureds using genetic testing have found ancestry to vary by region. Khoe-San ancestry is higher in inland regions and towards the north into the present-day Northern Cape. Although it is prevalent throughout the Cape, the partial Bantu-speaking ancestry (most predominantly Xhosa) increases going eastwards into present-day Eastern Cape. The European-related ancestry is highest along the coast. In Cape Town and the rest of the Western Cape province, the partial Asian ancestry is high and diverse due to the arrival of Asian and African slaves that mixed with Europeans (colonists, immigrants, tourists) and existing mixed race (Khoisan-European) which formed the modern-day Cape Coloureds and Cape Malay due to the creolisation of all those populations. At least 4 genetic studies indicate that the average Cape Coloured has an ancestry consisting of the following, with large variation between individuals:

Below are the approximate ranges for each ancestral component based on genetic studies and historical accounts:

Please note that this is not an exhaustive list, and individual results may vary. The ancestry of Cape Coloureds can be diverse and complex.

The genetic reference cluster term "Khoisan" itself refers to a colonially admixed population cluster, hence the concatenation, and is not a straightforward reference to ancient African pastoralist and hunter ancestry, which is often demarcated by the L0 haplogroup ancestry common in the general South African native population, which is also integral part of other aboriginal genetic reference cluster terms like "South-East African Bantu".

A separate Dutch Reformed Church, the Dutch Reformed Mission Church (DRMC), was formed in 1881 to serve the Cape Coloured Calvinist population separately from the Dutch Reformed Church in South Africa (NGK). It was merged in 1994 with the Dutch Reformed Church in Africa (DRCA, formed 1963) to form the Uniting Reformed Church in Southern Africa.^{[citation needed]}