PHF10

PHF10
Identifiers
Aliases	PHF10, BAF45A, XAP135, PHD finger protein 10, SMARCG4
External IDs	OMIM: 613069; MGI: 1919307; HomoloGene: 10112; GeneCards: PHF10; OMA:PHF10 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q27 Start 169,703,902 bp[1] End 169,725,566 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A2 Start 15,165,271 bp[2] End 15,181,535 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone left ovary right adrenal cortex right ovary left adrenal cortex C1 segment Skeletal muscle tissue of rectus abdominis gastric mucosa right lung body of pancreas Top expressed in fetal liver hematopoietic progenitor cell calvaria tail of embryo spermatocyte seminiferous tubule abdominal wall vas deferens human fetus ventricular zone primitive streak More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding histone acetyltransferase activity histone binding Cellular component nucleus npBAF complex histone acetyltransferase complex Biological process regulation of transcription, DNA-templated transcription, DNA-templated nervous system development histone acetylation negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55274 72057 Ensembl ENSG00000130024 ENSMUSG00000023883 UniProt Q8WUB8 Q9D8M7 RefSeq (mRNA) NM_133325 NM_018288 NM_024250 NM_001360983 RefSeq (protein) NP_060758 NP_579866 NP_077212 NP_001347912 Location (UCSC) Chr 6: 169.7 – 169.73 Mb Chr 17: 15.17 – 15.18 Mb PubMed search [3] [4]
Wikidata
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PHD finger protein 10 is a protein that in humans is encoded by the PHF10 gene.^[5][6]

This gene contains a predicted ORF that encodes a protein with two zinc finger domains. The function of the encoded protein is not known. Sequence analysis suggests that multiple alternatively spliced transcript variants are derived from this gene but the full-length nature of only two of them is known. These two splice variants encode different isoforms. A pseudogene for this gene is located on Xq28.^[6]

• PHF10+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

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