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Taurine

Taurine (/ˈtɔːrn/ ; IUPAC: 2-aminoethanesulfonic acid) is a naturally occurring organic compound with the chemical formula C2H7NO3S, and is a non-proteinogenic amino sulfonic acid widely distributed in mammalian tissues and organs. Structurally, by containing a sulfonic acid group instead of a carboxylic acid group, it is not involved in protein synthesis but is still usually referred to as an amino acid. As non-proteinogenic amino sulfonic acid, it is not encoded by the genetic code and is distinguished from the protein-building α-amino acids.

Taurine is a major constituent of bile and can be found in the large intestine, and is named after Latin taurus, meaning bull or ox, as it was first isolated from ox bile in 1827 by German scientists Friedrich Tiedemann and Leopold Gmelin.

Although taurine is abundant in human organs, it is not an essential human dietary nutrient and is not included among nutrients with a recommended intake level. Among the diverse pathways by which natural taurine can be biosynthesized, its human pathways (primarily in the human liver) are from cysteine and/or methionine.

Taurine is commonly sold as a dietary supplement, but there is no good clinical evidence that taurine supplements provide any benefit to human health. Taurine is used as a food additive to meet essential dietary intake levels for cats, and supplemental dietary support for dogs and poultry.

Taurine, named after Latin taurus, meaning bull or ox, was first isolated from ox bile in 1827 by German scientists Friedrich Tiedemann and Leopold Gmelin. Another German scientist Von H. Demarcay first used its common chemical name—Taurine—in 1838, derived from the Latin taurus (cognate to Ancient Greek ταῦρος, taûros) meaning bull or ox.It was subsequently identified in human bile in 1846 by Edmund Ronalds.[better source needed]

Taurine is widely distributed in nature, particularly in animal tissues.[better source needed] Moreover, it is abundant in nature, including in animal organs,[better source needed] and further, as substrates in the biosynthesis of bile salts. Taurine concentrations in human cells may derive from at least three processes:

It is not an essential human dietary nutrient, resulting in the absence of taurine from compounds having a Reference Daily Intake. Its role in human physiology is unknown.

Taurine is a major constituent of bile, and can be found in the large intestine.[citation needed] Its concentrations in land plants are low or undetectable, but up to a substantial wet weight has been found in algae.

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biologically significant aminosulfonic acid
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