Clorprenaline

Clorprenaline

Clinical data
Other names	Chlorprenaline; Isoprophenamine; Compound 20025; L-20025; 2-Chloro-β-hydroxy-N-isopropylphenethylamine
Drug class	Sympathomimetic; Bronchodilator; Sympathomimetic
Identifiers
IUPAC name 1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol
CAS Number	3811-25-4 5588-22-7 (hydrochloride)
PubChem CID	2810
ChemSpider	2708
UNII	3W4327W76O
KEGG	D01835
ChEBI	CHEBI:146226
ChEMBL	ChEMBL1902627
CompTox Dashboard (EPA)	DTXSID3048316
ECHA InfoCard	100.021.175
Chemical and physical data
Formula	C11H16ClNO
Molar mass	213.71 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)NCC(C1=CC=CC=C1Cl)O
InChI InChI=1S/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H3 Key:SSMSBSWKLKKXGG-UHFFFAOYSA-N

Clorprenaline (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name, BANTooltip British Approved Name), also known as isoprophenamine and known as clorprenaline hydrochloride (USANTooltip United States Adopted Name, JANTooltip Japanese Accepted Name) in the case of the hydrochloride salt, is a sympathomimetic and bronchodilator medication which is marketed in Japan.^[1][2][3] It acts as a β-adrenergic receptor agonist or as a β-sympathomimetic.^[2][3] Brand names of clorprenaline in Japan are numerous and include Asnormal, Bazarl, Bronchon, Clopinerin, Conselt, Cosmoline, Fusca, Kalutein, Pentadoll, Restanolon, and Troberin.^[2][1] The drug was first described in the literature by 1956.^[1][4]

1. ^ ^{a b c} Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 305. ISBN 978-1-4757-2085-3. Retrieved 17 October 2024.
2. ^ ^{a b c} Schweizerischer Apotheker-Verein (2004). Index Nominum: International Drug Directory. Medpharm Scientific Publishers. p. 309. ISBN 978-3-88763-101-7. Retrieved 17 October 2024.
3. ^ ^{a b} Morton IK, Hall JM (2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. p. 80. ISBN 978-94-011-4439-1. Retrieved 17 October 2024.
4. ^ Gibson WR, Powell CE, Swanson EE (December 1956). "The pharmacological action of 1-o-chlorophenyl-2-isopropylaminoethanol (isoprophenamine); a bronchodilator". J Am Pharm Assoc. 45 (12): 785–787. doi:10.1002/jps.3030451205. PMID 13376372.

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