In Greek mythology, an Amazonomachy (English translation: "Amazon battle"; plural, Amazonomachiai (Ancient Greek: Ἀμαζονομαχίαι) or Amazonomachies) is a mythological battle between the ancient Greeks and the Amazons, a nation of all-female warriors. The subject of Amazonomachies was popular in ancient Greek art and Roman art.

Throughout all of antiquity, the Amazons were regarded as a race of female warriors descended from Ares, fiercely independent and skilled in hunting, riding, archery, and warfare. They worshiped Ares and Artemis, respectively the god of war and the goddess of the hunt, and their geographic locations were notably associated with Scythia and the Asia Minor.

In Greek epic narratives, the Amazons were perceived to be non-Greek heroic figures who challenged the strength and masculinity of Greek heroes on the battlefield, such as Achilles, Bellerophon, Heracles (Hercules), Theseus, and the Athenians.

In the lost Greek epic Aethiopis, which was published in the 8th century BCE and is widely attributed to Arctinus of Miletus, Achilles fights and kills Penthesilea, the queen of the Amazons who came to aid Troy after the death of Hector. The oral myths and retellings of this epic fall of Troy referencing the Amazons contributed to Homer's Iliad and Odyssey.

During Hercules’ ninth labor, Hercules was given the task by Eurystheus to retrieve the royal girdle of the Amazon queen Hippolyta for his daughter. Though Hercules and the Amazons were originally open for peaceful negotiation, the malicious machinations of Hera incited a misunderstanding between the Amazons and Hercules, leading to a bloody battle in which the Amazons were ultimately defeated.

In some versions of the myth, Theseus had accompanied Hercules on his ninth labor and either eloped with or abducted Antiope, Hippolyta's sister (or Hippolyta herself). Antiope was then taken to Athens by Theseus, whom she married and bore a son, Hippolytus. As a result of the kidnapping, the Amazons invaded Greece, inciting the legendary Attic War between the Amazons and Athenians, which ended in the Amazons’ defeat.

Amazonomachy represents the Greek ideal of civilization. The Amazons were portrayed as a savage and barbaric race, while the Greeks were portrayed as a civilized race of human progress. According to Bruno Snell's view of Amazonomachy:

For the Greeks, the Titanomachy and the battle against the giants remained symbols of the victory which their own world had won over a strange universe; along with the battles against the Amazons and Centaurs they continue to signalize the Greek conquest of everything barbarous, of all monstrosity and grossness.