Plandemic is a trilogy of conspiracy theory films produced by Mikki Willis, promoting misinformation about the COVID-19 pandemic. They feature Judy Mikovits, a discredited American researcher and prominent anti-vaccine activist. The first video, Plandemic: The Hidden Agenda Behind Covid-19, was released on May 4, 2020, under Willis's production company Elevate Films. The second film, Plandemic Indoctornation, which includes more interviewees, was released on August 18 by Brian Rose's distributor of conspiracy theory related films, London Real. Later on June 3, 2023, Plandemic 3: The Great Awakening was released on The Highwire, a website devoted to conspiracy theories run by anti-vaccine activist Del Bigtree.

Upon its release, the first video went viral, becoming one of the most widespread pieces of COVID-19 misinformation, its popularity most attributed to online word-of-mouth. It was quickly removed by multiple online platforms, but this failed to stop its proliferation. The video also plausibly contributed to non-compliance with health protocols. Due to social media companies' preparedness for its release, Plandemic: Indoctornation received less attention.

Scientists and health professionals have criticized all the installments of the trilogy for their misleading claims, while Willis's filmmaking style employing various modes of persuasion has been cited as lending to a conspiratorial and brainwashing character of the film. Responding to the outcry directed at the first video, Willis expressed doubt about Mikovits's claims but continued to defend her, with Indoctornation being self-described as a "response video" to debunkers. The Great Awakening was also subject to debunking by fact-checkers.

The COVID-19 pandemic was caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in December 2019 in Wuhan, China, becoming a pandemic in 2020. Billions of people have contracted the disease and millions eventually died from it. As a result of the pandemic declaration, travel restrictions, social distancing measures, and many other precautions were enacted to try to prevent the spread of COVID-19 while vaccines were quickly developed and underwent phased distribution in most countries. Meanwhile, misinformation and conspiracy theories about the pandemic emerged, concerning the pandemic's scale, the virus' origin, diagnosis, and treatment. Among the popular conspiracy theory is that the virus is a bioweapon to control the population. Some people have claimed to have magical or faith-based cures for the disease.

Judy Anne Mikovits is a former American research scientist who is known for her discredited medical claims, such as the claim murine endogenous retroviruses are linked to chronic fatigue syndrome. Even prior to the pandemic, Mikovits was engaged in anti-vaccination activism and the promotion of conspiracy theories, and was accused of scientific misconduct. Prior to the release of Plandemic, Mikovits had expressed support for various COVID-19 conspiracy theories, claiming, for example, that the COVID-19 pandemic is a predictable flu season.

Mikki Willis is a former model and actor who had been making several New Age documentary films and conspiracy videos. At age 25, he founded the New York/Los Angeles Theater of the Arts, where he made several experimental plays, before making his feature debut film, Shoe Shine Boys (1996). He owns a production company, Elevate Films, which operates under the 501(c)(3) non-profit Elevate Foundation, founded in 2006. At one point, it also operated a namesake film festival. He was also co-director, co-cinematographer, and co-editor of the documentary Neurons to Nirvana (2013), which makes therapeutic claims on psychedelics. Residing in Ojai, California, Willis has a wife and business partner, Nadia Salamanca, as well as two sons. He has a family YouTube channel, Elevate Family, where one of his videos encouraging young boys to be unashamed of their cross-gender interests went viral. In 2023, it was reported they were planning to launch an alternative learning center.

The first installment of the trilogy, a 26-minute video titled Plandemic: The Hidden Agenda Behind Covid-19, promotes the conspiracist claim that vaccines are "a money-making enterprise that causes medical harm", exploring themes of the loss of free speech and free choice, also promoting parental autonomy against the pharmaceutical industry. It takes the form of an interview between Willis and Mikovits, who makes unsupported and false statements about SARS-CoV2, the disease it causes, and her own controversial history.

Fact-checking website PolitiFact highlighted eight false or misleading statements made in the video: