Bob
Have a question related to this hub?
Alice
Got something to say related to this hub?
Share it here.
3C (3C-x), also known as 4-substituted 3,5-dimethoxyamphetamines, substituted 3,4,5-trimethoxyamphetamine (3,4,5-TMA or TMA-1) analogues, or 3C-scalines, is a general name for the family of psychedelic amphetamines containing methoxy groups at the 3 and 5 positions of the benzene ring.[1][2] These compounds are analogues of 3,4,5-trimethoxyamphetamine (3,4,5-TMA or TMA-1).[1][2]
The 3C drugs are not the amphetamine counterparts of the 2C drugs, which are 4-substituted 2,5-dimethoxyphenethylamines.[1][2] Instead, the DOx drugs, which are 4-substituted 2,5-dimethoxyamphetamines, are the amphetamine counterparts of the 2C drugs.[1][2] The 3C drugs are the amphetamine counterparts of substituted mescaline analogues (4-substituted 3,5-dimethoxyphenethylamines).[1][2] Moreover, in terms of naming with the "3C" prefix, the 3C drugs are generally actually derivatives of TMA-1 with the 4-position methoxy group extended rather than having any 4-position substituent.[1][2] In this regard, they would be the 3,5-dimethoxyamphetamine counterparts of the 2C-O (2,4,5-trimethoxyphenethylamine) drugs (e.g., 2C-O-4) and the 2,4,5-trimethoxyamphetamine (2,4,5-TMA; TMA-2) derivatives (e.g., MEM).[3][4]
3C drugs have been developed and/or studied by Alexander Shulgin[1][2] and Daniel Trachsel,[5][6][4][7] among others.[8][9] The pharmacology of 3C drugs has been studied and described.[7][8]
{{cite journal}}: CS1 maint: article number as page number (link)