There are over 250 languages indigenous to Europe, and most belong to the Indo-European language family. Out of a total European population of 744 million as of 2018, some 94% are native speakers of an Indo-European language. The three largest phyla of the Indo-European language family in Europe are Romance, Germanic, and Slavic; they have more than 200 million speakers each, and together account for close to 90% of Europeans.

Smaller phyla of Indo-European found in Europe include Hellenic (Greek, c. 13 million), Baltic (c. 4.5 million), Albanian (c. 7.5 million), Celtic (c. 4 million), and Armenian (c. 4 million). Indo-Aryan, though a large subfamily of Indo-European, has a relatively small number of languages in Europe, and a small number of speakers (Romani, c. 1.5 million). However, a number of Indo-Aryan languages not native to Europe are spoken in Europe today.

Of the approximately 45 million Europeans speaking non-Indo-European languages, most speak languages within either the Uralic or Turkic families. Still smaller groups — such as Basque (language isolate), Semitic languages (Maltese, c. 0.5 million), and various languages of the Caucasus — account for less than 1% of the European population among them. Immigration has added sizeable communities of speakers of African and Asian languages, amounting to about 4% of the population, with Arabic being the most widely spoken of them.

Five languages have more than 50 million native speakers in Europe: Russian, German, French, Italian, and English. Russian is the most-spoken native language in Europe, and English has the largest number of speakers in total, including some 200 million speakers of English as a second or foreign language. (See English language in Europe.)

The Indo-European language family is descended from Proto-Indo-European, which is believed to have been spoken thousands of years ago. Early speakers of Indo-European daughter languages most likely expanded into Europe with the incipient Bronze Age, around 4,000 years ago (Bell-Beaker culture).

The Germanic languages make up the predominant language family in Western, Northern and Central Europe. It is estimated that over 500 million Europeans are speakers of Germanic languages, the largest groups being German (c. 95 million), English (c. 400 million)^{[citation needed]}, Dutch (c. 24 million), Swedish (c. 10 million), Danish (c. 6 million), Norwegian (c. 5 million) and Limburgish (c. 1.3 million).^{[citation needed]}

There are two extant major sub-divisions: West Germanic and North Germanic. A third group, East Germanic, is now extinct; the only known surviving East Germanic texts are written in the Gothic language. West Germanic is divided into Anglo-Frisian (including English), Low German, Low Franconian (including Dutch) and High German (including Standard German).

The Anglo-Frisian language family is now mostly represented by English (Anglic), descended from the Old English language spoken by the Anglo-Saxons: